69251-28-1

Basic information

• Product Name: 1-(5,6,7,8-tetrahydro-3-methoxy-5,5,8,8-tetramethyl-2-naphthyl)ethan-1-one
• Synonyms: 1-(5,6,7,8-tetrahydro-3-methoxy-5,5,8,8-tetramethyl-2-naphthyl)ethan-1-one;1-[(5,6,7,8-Tetrahydro-3-methoxy-5,5,8,8-tetramethylnaphthalen)-2-yl]ethanone
• CAS NO: 69251-28-1
• Molecular Formula: C₁₇H₂₄O₂
• Molecular Weight: 260.37126
• EINECS: 273-937-8
• Mol File: 69251-28-1.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 373.4°C at 760 mmHg
• Flash Point: 151.2°C
• Appearance: /
• Density: 0.969g/cm³
• Vapor Pressure: 8.98E-06mmHg at 25°C
• Refractive Index: 1.495
• CAS DataBase Reference: 1-(5,6,7,8-tetrahydro-3-methoxy-5,5,8,8-tetramethyl-2-naphthyl)ethan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(5,6,7,8-tetrahydro-3-methoxy-5,5,8,8-tetramethyl-2-naphthyl)ethan-1-one(69251-28-1)
• EPA Substance Registry System: 1-(5,6,7,8-tetrahydro-3-methoxy-5,5,8,8-tetramethyl-2-naphthyl)ethan-1-one(69251-28-1)

Safety Data

• Hazardous Substances Data: 69251-28-1(Hazardous Substances Data)

Usage

Class

Ketones

Structure

Contains a carbonyl group bonded to two alkyl groups
Has a naphthalene ring system
Has a methoxy group
Has multiple methyl groups

Uses

Fragrance and flavor industry
Valued for its aromatic properties

Potential applications

Pharmaceuticals
Other industries

Unique properties

Complex and unique structure
May have potential applications due to its unique structure and properties

InChI:InChI=1/C17H24O2/c1-11(18)12-9-13-14(10-15(12)19-6)17(4,5)8-7-16(13,2)3/h9-10H,7-8H2,1-6H3

Upstream product

• 74-83-9 methyl bromide 
• 102296-81-1 1-(3-hydroxy-5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)ethanone 
• 51510-70-4 1,2,3,4-tetrahydro-1,1,4,4-tetramethyl-6-methoxynaphthalene 
• 75-36-5 acetyl chloride 
• 6223-78-5 2,5-dichloro-2,5-dimethyl hexane 
• 22824-31-3 5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-ol 
• 108-95-2 phenol 
• 74-88-4 methyl iodide 

Relevant articles and documents

Discovery of tetrahydrotetramethylnaphthalene analogs as adult T-cell leukemia cell-selective proliferation inhibitors in a small chemical library constructed based on multi-template hypothesis

Adult T cell leukemia (ATL), caused by infection of human T-lymphotropic virus type 1 (HTLV-1), has a poor prognosis and curative therapy is unavailable, so it is important to find or design superior lead compounds for the drug treatment of ATL. We used our micro-reversed fragment-based drug design hypothesis and multi-template hypothesis to extract the tetrahydrotetramethylnaphthalene (TMN) skeleton from tamibarotene, a useful medicament for the treatment of acute promyelocytic leukemia (APL). Structural development of TMN yielded highly ATL cell-selective growth inhibitors, including 2-acetyl-3-hydroxy-5,6,7,8-tetrahydro-5,5,8,8-tetramethylnaphthalene (6). Structure-activity relationship analysis suggests the existence of a specific target molecule for ATL cell-selective inhibition of proliferation through G2 arrest.

5,6,7,8-tetrahydronaphthalen-2-yl 2,6-difluoroheptatrienoic acid derivatives having serum glucose reducing activity

Compounds of the formula where the variables have the meaning defined in the specification are capable of reducing serum glucose levels in diabetic mammals without the undesirable side effect of reducing serum thyroxine levels.

Identification of the first retinoid X receptor homodimer antagonist

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