69267-59-0 Usage
General Description
2-(4-aminophenyl)-1,2-dihydro-1,5-dimethyl-3H-pyrazol-3-one is a chemical compound that belongs to the pyrazolone class of organic compounds. It consists of a pyrazole ring with a phenyl group and an aminophenyl group attached at the 1 and 2 positions, and methyl groups at the 1 and 5 positions, giving it a 1,2-dihydro-1,5-dimethyl-3H-pyrazol-3-one structure. 2-(4-AMINOPHENYL)-1,2-DIHYDRO-1,5-DIMETHYL-3H-PYRAZOL-3-ONE has potential biological and pharmacological activities, including anti-inflammatory, analgesic, and antipyretic effects. It is often used as a building block in the synthesis of other pharmaceutical and biologically active compounds, and its properties make it an important target for research in the field of medicinal chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 69267-59-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,9,2,6 and 7 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 69267-59:
(7*6)+(6*9)+(5*2)+(4*6)+(3*7)+(2*5)+(1*9)=170
170 % 10 = 0
So 69267-59-0 is a valid CAS Registry Number.
InChI:InChI=1/C11H13N3O/c1-8-7-11(15)14(13(8)2)10-5-3-9(12)4-6-10/h3-7H,12H2,1-2H3
69267-59-0Relevant articles and documents
Pyrazolone methylamino piperidine derivatives as novel CCR3 antagonists
Pegurier, Cecile,Collart, Philippe,Danhaive, Pierre,Defays, Sabine,Gillard, Michel,Gilson, Frederic,Kogej, Thierry,Pasau, Patrick,Van Houtvin, Nathalie,Van Thuyne, Marc,van Keulen, BerendJan
, p. 4228 - 4231 (2008/02/09)
The discovery and optimization of a novel class of potent CCR3 antagonists is described. Details of synthesis and SAR are given together with some ADME properties of selected compounds. An optimal balance between activities, physicochemical properties, and in vitro metabolic stability was reached by the proper choice of substituents.
