69271-42-7

Basic information

• Product Name: ethanone, 1-(1-methyl-1H-indol-3-yl)-
• Synonyms: 1-(1-Methyl-1H-indazol-3-yl)ethanone;1-(1-Methyl-1H-indazol-3-yl);1-(1-methyl-1H-indol-3-yl)ethanone;ethanone, 1-(1-methyl-1H-indol-3-yl)-
• CAS NO: 69271-42-7
• Molecular Formula: C₁₀H₁₀N₂O
• Molecular Weight: 173.21114
• EINECS: 604-604-1
• Mol File: 69271-42-7.mol
• Article Data: 3

Chemical Properties

• Melting Point: 88-90 °C(Solv: hexane (110-54-3))
• Boiling Point: 313.1±15.0 °C(Predicted)
• Appearance: /
• Density: 1.18±0.1 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: -1.14±0.50(Predicted)
• CAS DataBase Reference: ethanone, 1-(1-methyl-1H-indol-3-yl)-(CAS DataBase Reference)
• NIST Chemistry Reference: ethanone, 1-(1-methyl-1H-indol-3-yl)-(69271-42-7)
• EPA Substance Registry System: ethanone, 1-(1-methyl-1H-indol-3-yl)-(69271-42-7)

Safety Data

• Hazardous Substances Data: 69271-42-7(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Tetrahedron Letters, 36, p. 4005, 1995 DOI: 10.1016/0040-4039(95)00699-D

Upstream product

• 109216-60-6 1-Methyl-1H-indazole-3-carboxylic acid methyl ester 
• 917-64-6 methyl magnesium iodide 
• 50890-83-0 1-methyl-1H-indazole-3-carboxylic acid 

Relevant articles and documents

A facile and simple synthesis of novel 2-(substituted)-5-(1-methyl-1H- indazol-3-yl)-oxazole derivatives

Novel 2-(substituted)-5-(1-methyl-1H-indazol-3-yl)-oxazoles (13) were synthesized in moderate yields, from 1-methyl-1H-Indazole 3-carboxylic acid (1), by converting it into a variety of amides (12) and further its heterocyclization. The structures of all the compounds have been elucidated on the basis of IR, 1H-NMR, and HRMS.

Indole and indazole derivatives, for the treatment and prophylaxis of cerebral disorders, their preparation and their use

Compounds of formula (I) : [in which R1 and R2 are each hydrogen or various organic groups, pis 0, 1, 2 or 3, U is -CO- or -CH(OR3)- where R3 is hydrogen or a hydroxy-protecting group, V is an optionally unsaturated aliphatic hydrocarbon group and W is a nitrogen-containing group] are useful in the treatment and prophylaxis of dementia especially of the Alzheimer's type.