69299-32-7Relevant articles and documents
Pd-catalyzed substitution of the oh group of nonderivatized allylic alcohols by phenols
Rukkijakan, Thanya,Akkarasamiyo, Sunisa,Sawadjoon, Supaporn,Samec, Joseph S. M.
, p. 4099 - 4104 (2018/04/14)
Nonactivated phenols have been employed as nucleophiles in the allylation of nonderivatized allylic alcohols to generate allylated phenolic ethers with water as the only byproduct. A Pd[BiPhePhos] catalyst was found to be reactive to give the O-allylated phenols in good to excellent yields in the presence of molecular sieves. The reactions are chemoselective in which the kinetically favored O-allylated products are formed exclusively over the thermodynamically favored C-allylated products.