693-93-6 Usage
Description
4-Methyloxazole is a heterocyclic compound with the molecular formula C4H5NO, featuring a five-membered oxazole ring with a methyl group attached to the fourth position. It is an important building block in the synthesis of various organic compounds and pharmaceuticals due to its unique chemical properties and reactivity.
Uses
Used in Pharmaceutical Industry:
4-Methyloxazole is used as a key intermediate in the synthesis of quinuclidine-based ligands, which serve as muscarinic cholinergic receptor agonists. These agonists are crucial in the development of drugs targeting neurological and cardiovascular disorders, as well as other therapeutic applications.
Additionally, 4-methyloxazole is utilized in the synthesis of other heterocyclic compounds, such as oxazoles and oxazolines. These compounds find applications in various industries, including pharmaceuticals, agrochemicals, and materials science, due to their diverse chemical properties and potential for further functionalization.
Check Digit Verification of cas no
The CAS Registry Mumber 693-93-6 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,9 and 3 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 693-93:
(5*6)+(4*9)+(3*3)+(2*9)+(1*3)=96
96 % 10 = 6
So 693-93-6 is a valid CAS Registry Number.
InChI:InChI=1/C4H5NO/c1-4-2-6-3-5-4/h2-3H,1H3
693-93-6Relevant articles and documents
Widely Exploited, Yet Unreported: Regiocontrolled Synthesis and the Suzuki–Miyaura Reactions of Bromooxazole Building Blocks
Solomin, Vitalii V.,Radchenko, Dmytro S.,Slobodyanyuk, Evgeniy Y.,Geraschenko, Oleksandr V.,Vashchenko, Bohdan V.,Grygorenko, Oleksandr O.
, p. 2884 - 2898 (2019/03/07)
An approach to synthesis of 2-, 4-, and 5-bromooxazoles is described. The method was optimized, and its scope was extended to all three isomeric parents, as well as various alkyl- and aryl-substituted bromooxazoles. It was found that direct regiocontrolled lithiation followed by reaction with electrophilic bromine source was common for all substrates and led exclusively to the target substituted 2-, 4- and 5-bromooxazoles on multigram scale. The utility of the multipurpose building blocks obtained in this work was demonstrated in the Suzuki–Miyaura cross-coupling reaction under parallel synthesis conditions.