6931-16-4 Usage
Description
2-Methoxyquinoline is an organic compound belonging to the quinoline family, characterized by the presence of a methoxy group attached to the 2nd position of the quinoline ring. It exhibits unique chemical properties and reactivity, making it a versatile molecule for various applications.
Uses
Used in Chemical Synthesis:
2-Methoxyquinoline is used as a key intermediate in the synthesis of various organic compounds, particularly in the preparation of pharmaceuticals, agrochemicals, and other specialty chemicals. Its reactivity and functional group make it a valuable building block for the development of new molecules with potential applications.
Used in Catalysts:
2-Methoxyquinoline is used as a catalyst in enol oxidation reactions, specifically in the preparation of isopentenal. Its ability to facilitate the enol oxidation process enhances the efficiency and selectivity of the reaction, leading to improved yields and reduced side reactions.
Used in Method for Preparation:
2-Methoxyquinoline is employed in a method for the preparation of isopentenal through enol oxidation. This method leverages the catalytic properties of 2-Methoxyquinoline to achieve the desired product with high efficiency and selectivity, making it a preferred approach in the synthesis of isopentenal and related compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 6931-16-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,9,3 and 1 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 6931-16:
(6*6)+(5*9)+(4*3)+(3*1)+(2*1)+(1*6)=104
104 % 10 = 4
So 6931-16-4 is a valid CAS Registry Number.
InChI:InChI=1/C10H9NO/c1-12-10-7-6-8-4-2-3-5-9(8)11-10/h2-7H,1H3
6931-16-4Relevant articles and documents
Tetramethylammonium Fluoride Alcohol Adducts for SNAr Fluorination
Bland, Douglas C.,Lee, So Jeong,Morales-Colón, Mariá T.,Sanford, Melanie S.,Scott, Peter J. H.,See, Yi Yang
supporting information, p. 4493 - 4498 (2021/06/28)
Nucleophilic aromatic fluorination (SNAr) is among the most common methods for the formation of C(sp2)-F bonds. Despite many recent advances, a long-standing limitation of these transformations is the requirement for rigorously dry, aprotic conditions to maintain the nucleophilicity of fluoride and suppress the generation of side products. This report addresses this challenge by leveraging tetramethylammonium fluoride alcohol adducts (Me4NF·ROH) as fluoride sources for SNAr fluorination. Through systematic tuning of the alcohol substituent (R), tetramethylammonium fluoride tert-amyl alcohol (Me4NF·t-AmylOH) was identified as an inexpensive, practical, and bench-stable reagent for SNAr fluorination under mild and convenient conditions (80 °C in DMSO, without the requirement for drying of reagents or solvent). A substrate scope of more than 50 (hetero) aryl halides and nitroarene electrophiles is demonstrated.
