693246-00-3

Basic information

• Product Name: Cyclopentanecarboxylic acid, 1-(1-methylethyl)-3-oxo-, phenylmethyl ester
• CAS NO: 693246-00-3
• Molecular Formula: C16H20O3
• Molecular Weight: 260.333
• Mol File: 693246-00-3.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Cyclopentanecarboxylic acid, 1-(1-methylethyl)-3-oxo-, phenylmethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclopentanecarboxylic acid, 1-(1-methylethyl)-3-oxo-, phenylmethyl ester(693246-00-3)
• EPA Substance Registry System: Cyclopentanecarboxylic acid, 1-(1-methylethyl)-3-oxo-, phenylmethyl ester(693246-00-3)

Safety Data

• Hazardous Substances Data: 693246-00-3(Hazardous Substances Data)

Upstream product

• 400770-75-4 1-isopropyl-3-oxocyclopentanoyl chloride 
• 100-51-6 benzyl alcohol 
• 400770-74-3 1-isopropyl-3,3-dimethoxyyclopentanecarboxylate 
• 625099-21-0 C₁₂H₂₂O₄ 
• 174195-95-0 tert-butyl 3-oxocyclopentane-1-carboxylate 
• 98-78-2 3-Oxo-cyclopentanecarboxylic acid 
• 782493-15-6 tert-butyl 1-isopropyl-3,3-dimethoxycyclopentanecarboxylate 
• 400771-20-2 tert-butyl 3,3-dimethoxycyclopentanecarboxylate 

Downstream Products

• 782493-13-4 (1S)-1-isopropyl-3-oxocyclopentanecarboxylic acid 
• 782493-18-9 (1S)-N-[2-tert-butoxy-5-(trifluoromethyl)benzyl]-1-isopropyl-3-oxocyclopentanecarboxamide 
• 782493-16-7 benzyl (1S)-1-isopropyl-3-oxocyclopentanecarboxylic acid 

Relevant articles and documents

Heterocyclic cyclopentyl tetrahydroisoquinoline and tetrahydropyridopyridine modulators of chemokine receptor activity

The present invention is directed to compounds of the formula I: Wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, X, n and the broken lines are as defined herein which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptor CCR-2.

2,6-Disubstituted piperiddines as modulators

The present invention is further directed to compounds of formula (I): wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R16, R17, R18, R19, R20, R21 and R22 are as defined herein) which are modulators of chemokine receptor activity and are useful in the prevention or treatment of certain inflammatory and immunoregulatory disorders and diseases, allergic diseases, atopic conditions including allergic rhinitis, dermatitis, conjunctivitis, and asthma, as well as autoimmune pathologies such as rheumatoid arthritis and atherosclerosis. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which chemokine receptors are involved.

BENZOXAZINYL-AMIDOCYCLOPENTYL-HETEROCYCLIC MODULATORS OF CHEMOKINE RECEPTORS

Cyclopentyl compounds linked to a benzoxazinyl group through an amido moiety utilizing the ring nitrogen of the benzoxazine, and further substituted with a heterocyclic moiety, such compounds represented by formula (I): which are used to modulate the CCR-