6933-25-1

Basic information

• Product Name: 2-thienyl p-tolyl ketone
• Synonyms: 2-thienyl p-tolyl ketone;(2-Thienyl)(4-methylphenyl) ketone;(4-Methylphenyl)-2-thienylmethanone;2-(4-Methylbenzoyl)thiophene;2-Thienyl(4-methylphenyl) ketone;4-Methylphenyl(2-thienyl) ketone;Einecs 230-057-9;(4-methylphenyl)-thiophen-2-ylmethanone
• CAS NO: 6933-25-1
• Molecular Formula: C₁₂H₁₀OS
• Molecular Weight: 202.2722
• EINECS: 230-057-9
• Mol File: 6933-25-1.mol
• Article Data: 44

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-thienyl p-tolyl ketone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-thienyl p-tolyl ketone(6933-25-1)
• EPA Substance Registry System: 2-thienyl p-tolyl ketone(6933-25-1)

Safety Data

• Hazardous Substances Data: 6933-25-1(Hazardous Substances Data)

Usage

InChI:InChI=1/C12H10OS/c1-9-4-6-10(7-5-9)12(13)11-3-2-8-14-11/h2-8H,1H3

Upstream product

• 188290-36-0 thiophene 
• 59046-28-5 p-toluoyl-1H-1,2,3-benzotriazole 
• 5271-67-0 2-Thiophenecarbonyl chloride 
• 66117-64-4 di(p-tolyl)borinic acid 
• 527-72-0 2-thiophenylcarboxylic acid 
• 6165-68-0 thiophene boronic acid 
• 201230-82-2 carbon monoxide 
• 624-31-7 4-tolyl iodide 
• 874-60-2 4-methyl-benzoyl chloride 
• 106-43-4 para-chlorotoluene 
• 75488-44-7 2-[1-(4-methylphenyl)ethenyl]thiophene 
• 17984-89-3 triethoxy(thiophen-2-yl)silane 
• 5720-05-8 4-methylphenylboronic acid 
• 108565-42-0 tri-(2-thienyl)-stibine 

Downstream Products

• 52841-35-7 (4-bromomethyl-phenyl)-thiophen-2-yl-methanone 
• 75488-44-7 2-[1-(4-methylphenyl)ethenyl]thiophene 
• 1202186-01-3 1-(4-methylphenyl)-1-(2-thienyl)-4-methyl-4-(tetrahydropyran-2-yloxy)-pent-2-yn-1-ol 
• 81541-46-0 3,6-Dioxo-4-[1-thiophen-2-yl-1-p-tolyl-meth-(E)-ylidene]-tetrahydro-pyridazine-1,2-dicarboxylic acid bis-methylamide 
• 81541-49-3 4-Morpholin-4-yl-4-oxo-2-[1-thiophen-2-yl-1-p-tolyl-meth-(E)-ylidene]-butyric acid methyl ester 
• 81541-48-2 4-Oxo-4-piperidin-1-yl-2-[1-thiophen-2-yl-1-p-tolyl-meth-(E)-ylidene]-butyric acid methyl ester 
• 81541-62-0 1-Phenyl-3-[1-thiophen-2-yl-1-p-tolyl-meth-(E)-ylidene]-pyrrolidine-2,5-dione 
• 81541-50-6 N-Ethyl-2-[1-thiophen-2-yl-1-p-tolyl-meth-(E)-ylidene]-succinamic acid methyl ester 
• 81541-47-1 (E)-2-Chlorocarbonylmethyl-3-thiophen-2-yl-3-p-tolyl-acrylic acid methyl ester 
• 81541-45-9 4-[1-Thiophen-2-yl-1-p-tolyl-meth-(E)-ylidene]-tetrahydro-pyridazine-3,6-dione 
• 81541-43-7 2-[1-Thiophen-2-yl-1-p-tolyl-meth-(E)-ylidene]-succinic acid 
• 81541-61-9 trans-(SC₄H₃/CO₂H)-3-carboxy-4-(p-tolyl)-4-(2'-thienyl)but-3-enoic acid anhydride 

Relevant articles and documents

Selective oxidation of alkenes to carbonyls under mild conditions

Herein, a practical and sustainable method for the synthesis of aldehydes, ketones, and carboxylic acids from an inexpensive olefinic feedstock is described. This transformation features very sustainable and mild conditions and utilizes commercially available and inexpensive tetrahydrofuran as the additive, molecular oxygen as the sole oxidant and water as the solvent. A wide range of substituted alkenes were found to be compatible, providing the corresponding carbonyl compounds in moderate-to-good yields. The control experiments demonstrated that a radical mechanism is responsible for the oxidation reaction.

Aryl aldiketone and synthesis method thereof

The invention discloses an aryl aldehyde ketone and a synthesis method thereof, wherein an aryl aldehyde is synthesized from cheap olefin as a raw material. A commercially available inexpensive olefin is used as a raw material, ether is used as an additive, molecular oxygen serves as a sole oxidizing agent, water is used as a solvent, and the aldehyde and ketone are synthesized by column chromatography under a photocatalytic condition. The invention has the advantages of mild reaction conditions, green and environmental protection, simple experimental operation, good reaction selectivity, high product yield and the like.

Highly efficient synthesis of aryl ketones by PEPPSI-palladium catalyzed acylative Suzuki coupling of amides with diarylborinic acids

An improved acylative cross-coupling of various N-methyl-N-tosyl amides with diarylborinic acids for synthesis of aryl ketones is developed. In most cases, aryl ketones could be obtained in excellent yields by using 1 mol% 2,6-diisopropylphenylimidazolylidene and 3-chloropyridine co-supported palladium chloride as catalyst in the presence of 3 equiv. K2CO3 as base in refluxing THF. The readily prepared and cost-effective substrates, N-methyl-N-tosylamides and diarylborinic acids, and the commercially available catalyst system promise a practical and efficient access to aryl ketones.