694479-56-6

Basic information

• Product Name: 6-methyl-2-oxo-1-[3-(trifluoromethyl)phenyl]pyridine-3-carboxylic acid
• Synonyms: 6-methyl-2-oxo-1-[3-(trifluoromethyl)phenyl]pyridine-3-carboxylic acid;6-METHYL-2-OXO-1-(3-(TRIFLUOROMETHYL)PHENYL)-1,2-DIHYDROPYRIDINE-3-CARBOXYLIC ACID
• CAS NO: 694479-56-6
• Molecular Formula: C₁₄H₁₀F₃NO₃
• Molecular Weight: 297.2293096
• Mol File: 694479-56-6.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 6-methyl-2-oxo-1-[3-(trifluoromethyl)phenyl]pyridine-3-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 6-methyl-2-oxo-1-[3-(trifluoromethyl)phenyl]pyridine-3-carboxylic acid(694479-56-6)
• EPA Substance Registry System: 6-methyl-2-oxo-1-[3-(trifluoromethyl)phenyl]pyridine-3-carboxylic acid(694479-56-6)

Safety Data

• Hazardous Substances Data: 694479-56-6(Hazardous Substances Data)

Upstream product

• 4652-27-1 4-methoxy-3-buten-2-one 
• 15386-86-4 ethyl 3-oxo-3-{[3-(trifluoromethyl)phenyl]amino}propanoate 
• 106109-76-6 methyl 3-oxo-3-(3-(trifluoromethyl)phenylamino)propanoate 
• 5436-21-5 acetylacetaldehyde dimethyl acetal 
• 98-16-8 3-trifluoromethylaniline 

Downstream Products

• 1281969-57-0 3-(5-(1-(4-cyanophenyl)-1H-pyrazol-5-yl)-6-methyl-2-oxo-1-(3-(trifluoromethyl)phenyl)-1,2-dihydropyridine-3-carboxamido)-N,N,N-trimethylpropan-1-aminium benzenesulfonate 
• 1281969-55-8 5-(1-(4-cyanophenyl)-1H-pyrazol-5-yl)-N-(3-(dimethylamino)propyl)-6-methyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-1,2-dihydropyridine-3-carboxamide 
• 1281969-58-1 N-[3-(dimethylamino)propyl]-5-iodo-6-methyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-1,2-dihydropyridine-3-carboxamide 
• 1281969-54-7 3-(5-(1-(4-cyanophenyl)-1H-pyrazol-5-yl)-6-methyl-2-oxo-1-(3-(trifluoromethyl)phenyl)-1,2-dihydropyridine-3-carboxamido)-N,N,N-trimethylpropan-1-aminium bromide 
• 1281969-56-9 3-(5-(1-(4-cyanophenyl)-1H-pyrazol-5-yl)-6-methyl-2-oxo-1-(3-(trifluoromethyl)phenyl)-1,2-dihydropyridine-3-carboxamido)-N,N,N-trimethylpropan-1-aminium acetate 
• 950857-05-3 C₃₃H₂₉Br₂F₆N₅O₄ 
• 950857-01-9 C₃₉H₄₃F₆N₇O₈ 
• 950857-56-4 C₂₀H₁₄F₃N₃O₅S 
• 950857-32-6 C₂₂H₂₂F₃NO₈ 
• 950857-41-7 C₂₄H₂₂F₃NO₅S 
• 950857-98-4 C₂₀H₁₄F₃N₃O₄S 
• 950857-50-8 C₂₀H₁₂F₃N₃O₃S 
• 950857-47-3 C₂₁H₁₄F₃N₃O₃S 
• 950857-59-7 C₂₂H₁₅F₃N₂O₃S 

Relevant articles and documents

ELASTASE INHIBITORS

Described herein are compounds, compositions, and methods of their use for the treatment of a lung or intestinal disease.

NOVEL SALT 628

6-Methyl-5-(1-methyl-1H-pyrazol-5-yl)-N-{[5-(methylsulfonyl)pyridin-2-yl]methyl}-2-oxo-1-[3-(trifluoromethyl)phenyl]-1,2-dihydropyridine-3-carboxamide 4-methylbenzenesulfonate and a novel crystalline form thereof are disclosed together with processes for preparing such salt and form, pharmaceutical compositions comprising such a salt and form, and the methods of treatment using such a salt and form.

2-PYRIDINE DERIVATIVES AS INHIBITORS OF NEUTROPHILE ELASTASE

The invention provides compounds of formula (I) wherein R1, R2, R3, R4, R5 and X are as defined in the specification and optical isomers, racemates and tautomers thereof, and pharmaceutically acceptab