6945-87-5

Basic information

• Product Name: 2-CHLORO-2-CYANO-BICYCLO(2,2,1)-HEPT-5-ENE
• Synonyms: 2-CHLOROBICYCLO[2.2.1]HEPT-5-ENE-2-CARBONITRILE;2-CHLORO-2-CYANO-BICYCLO(2,2,1)-HEPT-5-ENE;2-CHLORO-2-CYANO-BICYCLO(2,2,1)-HEPT-5-EN
• CAS NO: 6945-87-5
• Molecular Formula: C₈H₈ClN
• Molecular Weight: 153.60882
• Mol File: 6945-87-5.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 264 °C at 760 mmHg
• Flash Point: 116.5 °C
• Appearance: /
• Density: 1.24 g/cm³
• Vapor Pressure: 0.00996mmHg at 25°C
• Refractive Index: 1.553
• CAS DataBase Reference: 2-CHLORO-2-CYANO-BICYCLO(2,2,1)-HEPT-5-ENE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CHLORO-2-CYANO-BICYCLO(2,2,1)-HEPT-5-ENE(6945-87-5)
• EPA Substance Registry System: 2-CHLORO-2-CYANO-BICYCLO(2,2,1)-HEPT-5-ENE(6945-87-5)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 6945-87-5(Hazardous Substances Data)

Usage

General Description

2-Chloro-2-cyano-bicyclo(2,2,1)-hept-5-ene is a chemical compound with the molecular formula C8H8ClN. It is a bicyclic compound, containing both a chlorine and a cyano group, and is classified as an unsaturated heterocyclic compound. This chemical is commonly used as an intermediate in the synthesis of various pharmaceuticals and agrochemicals due to its unique structural properties. It is also used as a building block in the production of specialty polymers and other organic compounds. 2-Chloro-2-cyano-bicyclo(2,2,1)-hept-5-ene is considered to be a versatile and valuable chemical building block in the synthesis of various complex organic compounds.

InChI:InChI=1/C8H8ClN/c9-8(5-10)4-6-1-2-7(8)3-6/h1-2,6-7H,3-4H2

Upstream product

• 542-92-7 cyclopenta-1,3-diene 
• 920-37-6 2-Chloroacrylonitrile 
• 77-73-6 bi(cyclopentadiene) 
• 2890-96-2 5-norbornene-2-carbonitrile 

Downstream Products

• 83205-33-8 (1S,2S,4R,5S,6S)-2,5-Dichloro-6-phenylselanyl-bicyclo[2.2.1]heptane-2-carbonitrile 
• 83205-33-8 6-exo-benzeneselenenyl-2-endo,5-endo-dichlorobicyclo<2.2.1>heptane-2-exo-carbonitrile 
• 694-98-4 norborn-5-en-2-one 
• 497-38-1 2-norbornanone 
• 125107-71-3 ((1R,2S,6S,7R)-3,5-Dioxo-4-phenyl-4-aza-tricyclo[5.2.1.0^2,6]dec-8-en-1-yl)-acetonitrile 
• 125107-72-4 ((1R,2R,6S,7S,10R)-3,5-Dioxo-4-phenyl-4-aza-tricyclo[5.2.1.0^2,6]dec-8-en-10-yl)-acetonitrile 

Relevant articles and documents

Microwave-assisted solvent-free Diels-Alder reaction - A fast and simple route to various 5,6-substituted norbornenes and polychlorinated norbornenes

A series of 5,6-substituted norbornenes and 5,6-substituted polychlorinated norbornenes was prepared by using a microwave-assisted Diels-Alder reaction. This procedure proved very versatile, fast, and with an easy workup step, and therefore suitable even for large-scale synthesis. Georg Thieme Verlag Stuttgart · New York.

Ring-rearrangement metathesis of substituted 2-aminonorbornenes

In this report we describe the ring-rearrangement metathesis of 2-aminonorbornene derivatives. An efficient ruthenium-catalysed metathesis reaction occurs with a wide range of pendent alkenes and alkynes to generate bicyclic amines and amides. Georg Thieme Verlag Stuttgart.

PHARMACEUTICAL COMPOSITIONS AND METHODS FOR RELIEVING PAIN AND TREATING CENTRAL NERVOUS SYSTEM DISORDERS

Patients susceptible to or suffering from disorders, such as central nervous system disorders, which are characterized by an alteration in normal neurotransmitter release, such as dopamine release (e.g., Parkinsonism, Parkinson's Disease, Tourette's Syndrome, attention deficient disorder, or schizophrenia), are treated by administering a compound of Formulas (1 or 2), as described herein. The compounds of Formulas (1 and 2) are also useful for treating pain, and treating drug addiction, nicotine addiction, and/or obesity. The compounds can exist as individual stereoisomers, racemic mixtures, diastereomers and the like.