6947-77-9

Basic information

• Product Name: 5,7-diazaspiro[2.5]octane-4,6,8-trione
• CAS NO: 6947-77-9
• Molecular Formula: C₆H₆N₂O₃
• Molecular Weight: 154.1234
• Mol File: 6947-77-9.mol
• Article Data: 4

Chemical Properties

• Density: 1.57g/cm³
• Refractive Index: 1.597
• CAS DataBase Reference: 5,7-diazaspiro[2.5]octane-4,6,8-trione(CAS DataBase Reference)
• NIST Chemistry Reference: 5,7-diazaspiro[2.5]octane-4,6,8-trione(6947-77-9)
• EPA Substance Registry System: 5,7-diazaspiro[2.5]octane-4,6,8-trione(6947-77-9)

Safety Data

• Hazardous Substances Data: 6947-77-9(Hazardous Substances Data)

Upstream product

• 67-52-7 BARBITURIC ACID 
• 106-93-4 ethylene dibromide 
• 1559-02-0 diethyl cyclopropane-1,1-dicarboxylate 
• 57-13-6 urea 

Downstream Products

• 598-10-7 cyclopropane-1,1-dicarboxylic acid 

Relevant articles and documents

A simple synthesis of 5-spirobarbituric acids and transformations of spirocyclopropanobarbiturates to 5-substituted barbiturates

The reactions of barbituric acid and its 1,3-dimethyl derivative with 1,2-dibromoethane, 1,4-dibromobutane, 1,5-dibromopentane and 1,2-bis[bromomethyl] benzene in DMF-K2CO3 (base), TBAHSO4 (catalyst) provide 5-spirobarbitu

Latent Inhibitors. Part 7. Inhibition of Dihydro-orotate Dehydrogenase by Spirocyclopropanobarbiturates

A series of 5-spirocyclopropanobarbiturates bearing alkyl and aryl substituents on the cyclopropane ring has been synthesized.Dihydro-orotate dehydrogenase from Clostridium oroticum was shown to be inhibited by these compounds.A related series of 5-member