695224-56-7

Basic information

• Product Name: 5-phenyl-3-(2-thienyl)-1,2,4-oxadiazole
• Synonyms: 5-phenyl-3-(2-thienyl)-1,2,4-oxadiazole
• CAS NO: 695224-56-7
• Molecular Weight: 228.274
• Mol File: 695224-56-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-phenyl-3-(2-thienyl)-1,2,4-oxadiazole(CAS DataBase Reference)
• NIST Chemistry Reference: 5-phenyl-3-(2-thienyl)-1,2,4-oxadiazole(695224-56-7)
• EPA Substance Registry System: 5-phenyl-3-(2-thienyl)-1,2,4-oxadiazole(695224-56-7)

Safety Data

• Hazardous Substances Data: 695224-56-7(Hazardous Substances Data)

Upstream product

• 100-46-9 benzylamine 
• 29683-84-9 thiophene-2-carbaldehyde oxime 

Relevant articles and documents

Synthesis of 1,2,4-Oxadiazoles via DDQ-Mediated Oxidative Cyclization of Amidoximes

An oxidative cyclization of amidoximes to form 1,2,4-oxadiazoles, mediated by 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ), is described. A range of alkyl, aryl, and heteroaryl substrates are tolerated under these conditions. This reaction serves as an alternate approach for the synthesis of functionally diverse oxadiazoles via a rapid and straightforward synthetic procedure.