6961-46-2

Basic information

• Product Name: idrocilamide
• Synonyms: idrocilamide;brolitene;LCB-29;N-(2-Hydroxyethyl)-3-phenylpropenamide;Srilane;Talval;N-(2-Hydroxyethyl)-3-phenyl-2-propenamide
• CAS NO: 6961-46-2
• Molecular Formula: C₁₁H₁₃NO₂
• Molecular Weight: 191.229
• EINECS: 230-155-1
• Mol File: 6961-46-2.mol
• Article Data: 4

Chemical Properties

• Melting Point: 100-102°
• Boiling Point: 439.4 °C at 760 mmHg
• Flash Point: 219.5 °C
• Appearance: /
• Density: 1.146 g/cm³
• Vapor Pressure: 1.7E-08mmHg at 25°C
• Refractive Index: 1.593
• Storage Temp.: -20°C Freezer, Under inert atmosphere
• Solubility: Chloroform (Slightly, Sonicated), Methanol (Slightly)
• CAS DataBase Reference: idrocilamide(CAS DataBase Reference)
• NIST Chemistry Reference: idrocilamide(6961-46-2)
• EPA Substance Registry System: idrocilamide(6961-46-2)

Safety Data

• Hazardous Substances Data: 6961-46-2(Hazardous Substances Data)

Usage

Description

Idrocilamide, also known as idrocilamida, is a compound that belongs to the class of palmitoylethanolamide derivatives. It is characterized by its potential pharmacological properties and applications in various therapeutic areas.

Uses

Used in Pharmaceutical Industry:
Idrocilamide is used as an anticonvulsant and antidepressant agent for its potential therapeutic effects in managing seizures and depressive disorders. Its mechanism of action and pharmacological profile make it a promising candidate for further research and development in the treatment of neurological conditions.
Please note that the provided materials only mention the use of idrocilamide as an anticonvulsant and antidepressant. If there are other applications or uses in different industries, they are not mentioned in the given materials.

InChI:InChI=1/C11H13NO2/c13-9-8-12-11(14)7-6-10-4-2-1-3-5-10/h1-7,13H,8-9H2,(H,12,14)/b7-6+

Upstream product

• 141-43-5 ethanolamine 
• 621-82-9 Cinnamic acid 
• 102-92-1 cinnamoyl chloride 
• 104-55-2 3-phenyl-propenal 

Downstream Products

• 65057-00-3 5-Benzoyl-3-indancarbonsaeure-2'-zimtsaeureamidoethylester 

Relevant articles and documents

TASTE-MODIFYING COMPOUNDS AND USES THEREOF

The present disclosure generally relates to compounds useful as taste modifiers, particularly as compounds useful for enhancing umami taste, and their use in various comestible products, such as food and beverage products.

Synthesis and antidepressant-like action of N-(2-hydroxyethyl) cinnamamide derivatives in mice

This study described the chemical synthesis and pharmacological evaluation of a series of N-(2-hydroxyethyl) cinnamamide derivatives. The structures of them were characterized by IR, 1H-NMR, MS and elemental analysis. Their antidepressant activities were evaluated by the forced swimming test (FST) and tail suspension test (TST). Pharmacological results of these compounds showed that some of them, given orally, significantly reduced the immobility time in the FST and TST, indicating the antidepressant-like action. Among them, compounds N-(2-hydroxyethyl)cinnamamide (1g), (E)-3-(4-hydroxy-3- methoxyphenyl)-N-(2-hydroxyethyl)acrylamide (1i) and (E)-N-(2-hydroxyethyl)-3- (3-hydroxyphenyl)acrylamide (1n), active in the two models, were considered as the most promising compounds in this study. Springer Science+Business Media, LLC 2010.