6962-60-3

Basic information

• Product Name: 2-Benzylbenzoic acid methyl ester
• Synonyms: 2-Benzylbenzoic acid methyl ester
• CAS NO: 6962-60-3
• Molecular Formula: C₁₅H₁₄O₂
• Molecular Weight: 226.2705
• Mol File: 6962-60-3.mol
• Article Data: 14

Chemical Properties

• Boiling Point: 347.5°Cat760mmHg
• Flash Point: 156.5°C
• Appearance: /
• Density: 1.094g/cm³
• Vapor Pressure: 5.37E-05mmHg at 25°C
• Refractive Index: 1.565
• CAS DataBase Reference: 2-Benzylbenzoic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Benzylbenzoic acid methyl ester(6962-60-3)
• EPA Substance Registry System: 2-Benzylbenzoic acid methyl ester(6962-60-3)

Safety Data

• Hazardous Substances Data: 6962-60-3(Hazardous Substances Data)

Usage

InChI:InChI=1/C15H14O2/c1-17-15(16)14-10-6-5-9-13(14)11-12-7-3-2-4-8-12/h2-10H,11H2,1H3

Upstream product

• 67-56-1 methanol 
• 612-35-1 2-Benzylbenzoic acid 
• 606-28-0 methyl o-benzoylbenzoate 
• 100-52-7 benzaldehyde 
• 100-51-6 benzyl alcohol 
• 100-53-8 phenylmethanethiol 
• 943868-13-1 4-benzylsulfanyl-2,3,5,6-tetrafluoropyridine 
• 619-42-1 4-methoxycarbonylphenyl bromide 
• 610-94-6 2-bromobenzoic acid methyl ester 
• 59151-16-5 2-bromobenzaldehyde-α-d₁ 
• 1666-17-7 benzaldehyde p-toluenesulfonylhydrazone 
• 3375-31-3 palladium diacetate 
• 6630-33-7 ortho-bromobenzaldehyde 
• 1576-35-8 toluene-4-sulfonic acid hydrazide 

Downstream Products

• 148991-82-6 2-benzyl-N-methoxybenzamide 
• 612-35-1 2-Benzylbenzoic acid 
• 32832-95-4 2-benzylbenzaldehyde 
• 66827-79-0 10,10-Dimethyl-9,10-dihydroanthracene-9-carboxamide 
• 7477-39-6 9,9-diphenyl-9,10-dihydroanthracene 
• 88689-60-5 2,2'-dibenzyl-bibenzyl 
• 36374-49-9 2-(2-benzylphenyl)acetic acid 
• 55276-42-1 2-benzylbenzyl bromide 
• 1586-03-4 2-(2-benzylphenyl)acetonitrile 
• 123570-21-8 2-Benzyl-<α,α-D2>-benzylalkohol 
• 57732-89-5 ortho-benzyl-α,α'-dimethylbenzyl alcohol 
• 60456-75-9 1,1'-diphenyl-1H,1'H-[1,1']biisobenzofuranyl-3,3'-dione 
• 1586-00-1 2-(benzyl)benzyl alcohol 
• 102876-41-5 Hydroxy-diphenyl-(2-benzyl-phenyl)-methan 

Relevant articles and documents

Nickel-Catalyzed Reductive Cross-Coupling of Benzylic Sulfonium Salts with Aryl Iodides

A nickel-catalyzed cross-electrophile coupling of benzylic sulfonium salts with aryl iodides has been developed, providing direct access to diarylalkanes from readily available and stable coupling partners. Preliminary mechanistic studies suggest that the C-S bond cleavage proceeds through a single-electron transfer process to generate a benzylic radical.

Nickel-Catalyzed Electrochemical C(sp3)?C(sp2) Cross-Coupling Reactions of Benzyl Trifluoroborate and Organic Halides**

Reported here is the redox neutral electrochemical C(sp2)?C(sp3) cross-coupling reaction of bench-stable aryl halides or β-bromostyrene (electrophiles) and benzylic trifluoroborates (nucleophiles) using nonprecious, bench-stable NiCl2?glyme/polypyridine catalysts in an undivided cell configuration under ambient conditions. The broad reaction scope and good yields of the Ni-catalyzed electrochemical coupling reactions were confirmed by 50 examples of aryl/β-styrenyl chloride/bromide and benzylic trifluoroborates. Potential applications were demonstrated by electrosynthesis and late-stage functionalization of pharmaceuticals and natural amino acid modification, and three reactions were run on gram-scale in a flow-cell electrolyzer. The electrochemical C?C cross-coupling reactions proceed through an unconventional radical transmetalation mechanism. This method is highly productive and expected to find wide-spread applications in organic synthesis.

Palladium-Catalyzed Three-Component Coupling Reaction of o-Bromobenzaldehyde, N-Tosylhydrazone, and Methanol

A ligand-controlled palladium-catalyzed three-component reaction of o-bromobenzaldehyde, N-tosylhydrazone, and methanol is described. This reaction uses readily available compounds as starting materials while displaying a broad substrate scope and good functional group compatibility.