6963-40-2

Basic information

• Product Name: 2-ethoxyethyl acetoacetate
• Synonyms: 2-ethoxyethyl acetoacetate;3-Oxobutyric acid 2-ethoxyethyl ester;Ai3-06509;Butanoic acid, 3-oxo-, 2-ethoxyethyl ester;Einecs 230-160-9
• CAS NO: 6963-40-2
• Molecular Formula: C₈H₁₄O₄
• Molecular Weight: 174.19436
• EINECS: 230-160-9
• Mol File: 6963-40-2.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 247.1°C at 760 mmHg
• Flash Point: 102.6°C
• Appearance: /
• Density: 1.039g/cm³
• Vapor Pressure: 0.0261mmHg at 25°C
• Refractive Index: 1.422
• CAS DataBase Reference: 2-ethoxyethyl acetoacetate(CAS DataBase Reference)
• NIST Chemistry Reference: 2-ethoxyethyl acetoacetate(6963-40-2)
• EPA Substance Registry System: 2-ethoxyethyl acetoacetate(6963-40-2)

Safety Data

• Hazardous Substances Data: 6963-40-2(Hazardous Substances Data)

Usage

General Description

2-Ethoxyethyl acetoacetate is a chemical compound that is commonly used as a solvent in various industrial processes such as paints, coatings, and inks. It is a colorless liquid with a sweet and fruity odor, and it is flammable and is incompatible with strong oxidizing agents. 2-ethoxyethyl acetoacetate has the chemical formula C8H14O4 and is also known by the names ethyl 3-oxobutanoate and acetoacetic acid ethyl ester. It is primarily used as a reactive diluent in the production of polyurethane coatings and adhesives, as well as in the synthesis of pharmaceuticals, agrochemicals, and fragrances. Additionally, it can act as a ligand in coordination chemistry. Overall, 2-ethoxyethyl acetoacetate is a versatile chemical that finds applications in various industries due to its solvency and reactivity.

InChI:InChI=1/C8H14O4/c1-3-11-4-5-12-8(10)6-7(2)9/h3-6H2,1-2H3

Upstream product

• 674-82-8 4-methyleneoxetan-2-one 
• 110-80-5 2-ethoxy-ethanol 

Downstream Products

• 62760-00-3 2-ethoxyethyl 2-methyl-4-(2-nitrophenyl)-5-ethoxycarbonyl-6-diethoxymethyl-1,4-dihydropyridine-3-carboxylate 
• 142619-07-6 β-ethoxyethyl 2-(m-nitrobenzylidene)acetoacetate 
• 22609-72-9 bis(2-ethoxyethyl) 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate 
• 62760-08-1 2-(3-Nitrobenzyliden)acetessigsaeure-(2-ethoxyethyl)ester 
• 75206-26-7 2-[1-(2-Cyano-phenyl)-meth-(E)-ylidene]-3-oxo-butyric acid 2-ethoxy-ethyl ester 
• 75530-27-7 3-Oxo-2-[1-(2-trifluoromethyl-phenyl)-meth-(E)-ylidene]-butyric acid 2-ethoxy-ethyl ester 
• 52452-35-4 4-Ethoxy-2-oxo-6-p-tolyl-cyclohex-3-enecarboxylic acid 2-ethoxy-ethyl ester 
• 75535-92-1 2-Diethoxymethyl-6-methyl-4-(2-trifluoromethyl-phenyl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid 5-(2-ethoxy-ethyl) ester 3-ethyl ester 
• 75206-35-8 4-(2-Cyano-phenyl)-2-diethoxymethyl-6-methyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 5-(2-ethoxy-ethyl) ester 3-ethyl ester 
• 75530-91-5 2-Cyano-6-methyl-4-(2-trifluoromethyl-phenyl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid 5-(2-ethoxy-ethyl) ester 3-ethyl ester 
• 75530-57-3 2-Formyl-6-methyl-4-(2-trifluoromethyl-phenyl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid 5-(2-ethoxy-ethyl) ester 3-ethyl ester 
• 75206-46-1 2-Cyano-4-(2-cyano-phenyl)-6-methyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 5-(2-ethoxy-ethyl) ester 3-ethyl ester 
• 75206-41-6 4-(2-Cyano-phenyl)-2-formyl-6-methyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 5-(2-ethoxy-ethyl) ester 3-ethyl ester 
• 75206-50-7 4-(2-Cyano-phenyl)-2-hydroxymethyl-6-methyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 5-(2-ethoxy-ethyl) ester 3-ethyl ester 

Relevant articles and documents

Synthesis and antihypertensive activities of new 1,4-dihydropyridine derivatives containing a nitrooxy moiety at the 3-ester position

The synthesis of a new series of dihydropyridines containing a nitrooxy moiety at the 3-ester position is described. The antihypertensive activity of the compounds was examined and compared with that of nifedipine; some of them were relatively potent. The structure-activity relationship is also discussed.

The influence of the ester function on the vasodilating activity of 1,4-dihydro-2,6-dimethyl-4-nitrophenyl-pyridine-3,5-dicarboxylates

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