6969-02-4

Basic information

• Product Name: [3-(4-methoxyphenyl)oxiran-2-yl](phenyl)methanone
• Synonyms: [3-(4-Methoxy-phenyl)-oxiranyl]-phenyl-methanone; Methanone, (3-(4-methoxyphenyl)oxiranyl)phenyl-, trans-; Propiophenone, 2,3-epoxy-3-(p-methoxyphenyl)-, trans-
• CAS NO: 6969-02-4
• Molecular Formula: C₁₆H₁₄O₃
• Molecular Weight: 254.2806
• Mol File: 6969-02-4.mol
• Article Data: 26

Chemical Properties

• Boiling Point: 411°C at 760 mmHg
• Flash Point: 194°C
• Density: 1.213g/cm³
• Vapor Pressure: 5.77E-07mmHg at 25°C
• Refractive Index: 1.599
• CAS DataBase Reference: [3-(4-methoxyphenyl)oxiran-2-yl](phenyl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: [3-(4-methoxyphenyl)oxiran-2-yl](phenyl)methanone(6969-02-4)
• EPA Substance Registry System: [3-(4-methoxyphenyl)oxiran-2-yl](phenyl)methanone(6969-02-4)

Safety Data

• Hazardous Substances Data: 6969-02-4(Hazardous Substances Data)

Usage

Description

[3-(4-methoxyphenyl)oxiran-2-yl](phenyl)methanone is a complex organic compound characterized by a molecular structure that includes a phenyl ring, an oxirane group, and a ketone group. The oxirane group is connected to a 4-methoxyphenyl group, while the ketone group is linked to another phenyl group. As a ketone derivative of a substituted oxirane, this compound holds promise for various applications in the realms of organic synthesis and pharmaceutical research.

Uses

Used in Organic Synthesis:
[3-(4-methoxyphenyl)oxiran-2-yl](phenyl)methanone serves as an important intermediate in organic synthesis, particularly for the creation of complex molecular structures. Its unique arrangement of functional groups allows for a range of chemical reactions, making it a valuable component in the synthesis of various organic compounds.
Used in Pharmaceutical Research:
In the pharmaceutical industry, [3-(4-methoxyphenyl)oxiran-2-yl](phenyl)methanone is utilized as a key building block for the development of novel drugs. [3-(4-methoxyphenyl)oxiran-2-yl](phenyl)methanone's functional groups can be manipulated to create new molecules with potential therapeutic properties, contributing to the advancement of medical treatments for various diseases and conditions.
Used in Chemical Research:
[3-(4-methoxyphenyl)oxiran-2-yl](phenyl)methanone also plays a significant role in chemical research, where it can be employed to study the reactivity and behavior of different functional groups. Understanding these properties can lead to the discovery of new chemical reactions and the development of innovative materials and compounds.

Upstream product

• 22252-15-9 trans-4-methoxychalcone 
• 959-33-1 3-(4-methoxyphenyl)-1-phenylprop-2-en-1-one 
• 637-69-4 4-Methoxystyrene 
• 100-52-7 benzaldehyde 
• 123-11-5 4-methoxy-benzaldehyde 
• 98-86-2 acetophenone 
• 532-27-4 1-chloroacetophenone 
• 70-11-1 α-bromoacetophenone 

Downstream Products

• 80883-97-2 1-(p-Sulfamylphenyl)-4-hydroxy-3-phenyl-5-p-methoxyphenyl-2-pyrazoline 
• 106002-85-1 3-(4-methoxyphenyl)-1-phenylpropane-1,2-dione 
• 766-76-7 benzoate 
• 71-47-6 formate 
• 123-11-5 4-methoxy-benzaldehyde 
• 76246-85-0 erythro-2-(4-methoxyphenyl)-1-phenyl-1,3-propanediol 
• 371961-34-1 2-hydroxy-3-methoxy-3-(4-methoxy-phenyl)-1-phenyl-propan-1-one 
• 34082-43-4 2-methoxybenzil 
• 25826-75-9 2-(4-methoxyphenyl)-3-oxo-3-phenylpropanal 
• 86387-70-4 2-(p-methoxyphenyl)-1-phenylprop-2-en-1-one 
• 1430342-25-8 2-(4-methoxyphenyl)-3-hydroxy-1-phenylpropan-1-one 
• 6956-56-5 2,2-dimethoxy-1-phenylethanone 
• 1422445-12-2 (S)-2-hydroxy-3,3-bis(4-methoxyphenyl)-1-phenylpropan-1-one 
• 71344-43-9 (1-(4-methoxyphenyl)naphtho[2,1-b]furan-2-yl)(phenyl)methanone 

Relevant articles and documents

Application of chiral TADDOL ligand and rare earth metal amide in combined catalysis of asymmetric reaction

The invention relates to application of chiral TADDOL ligand and rare earth metal amide in combined catalysis of asymmetric epoxidation reaction of chalcone compounds. According to the application, alpha, beta-unsaturated ketone shown in a formula (1) and tert-butyl hydroperoxide react in the presence of organic alkali under the combined catalytic action of a chiral TADDOL ligand shown in a formula (3) and rare earth metal amide in an anhydrous, oxygen-free and protective atmosphere to obtain the chiral epoxy compound shown in the formula (2) after the reaction is completed, wherein R1 is selected from hydrogen, alkyl, halogen, alkoxy, trifluoromethyl, nitro or cyano, R2 is selected from phenyl, substituted phenyl, naphthyl, furyl or thienyl; R3 and R4 are respectively and independently selected from alkyl, phenyl or R3 and R4 and carbon atoms connected with R3 and R4 form naphthenic base; Ar is phenyl, substituted phenyl, biphenyl or naphthyl; the molecular formula of the rare earth metal amide is RE [N (SiMe3) 2] 3. The method has the advantages of wide substrate application range, high yield and high enantioselectivity.

A highly enantioselective asymmetric Darzens reaction catalysed by proline based efficient organocatalysts for the synthesis of di- and tri-substituted epoxides

A new class of easily available and readily tunable proline based chiral organocatalysts was found to efficiently catalyse an unprecedented highly enantioselective asymmetric Darzens reaction of α-chloroketones and substituted α-chloroketones with various

Metal-Free and Efficient Epoxidation of α,β-Unsaturated Ketones with 1,1,2,2-Tetrahydroperoxy-1,2-Diphenylethane as a Powerful Solid Oxidant

1,1,2,2-Tetrahydroperoxy-1,2-diphenylethane was used for the efficient and metal-free epoxidation of various α,β-unsaturated ketones, carried out under mild alkaline conditions at room temperature.