69728-92-3

Basic information

• Product Name: Benzenesulfonamide, 4-(acetyloxy)-
• CAS NO: 69728-92-3
• Molecular Formula: C8H9NO4S
• Molecular Weight: 215.23
• Mol File: 69728-92-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Benzenesulfonamide, 4-(acetyloxy)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenesulfonamide, 4-(acetyloxy)-(69728-92-3)
• EPA Substance Registry System: Benzenesulfonamide, 4-(acetyloxy)-(69728-92-3)

Safety Data

• Hazardous Substances Data: 69728-92-3(Hazardous Substances Data)

Upstream product

• 63-74-1 sulfanilamide 
• 1576-43-8 4-hydroxybenzenesulphonamide 
• 108-24-7 acetic anhydride 
• 75-36-5 acetyl chloride 

Downstream Products

• 99982-76-0 1-(4-hydroxybenzenesulfonyl)-3-butyl urea 
• 25210-29-1 acetyl-(4-hydroxy-benzenesulfonyl)-amine 

Relevant articles and documents

FURAN DERIVATIVES AS EP4 RECEPTOR ANTAGONISTS

A compound of formula: (I); or a salt, solvate and chemically protected form thereof, wherein one of R2 and R5 is: (i) H or an optionally substituted C1-4 alkyl group; or (ii)an optionally substituted C5-7 aryl;

Synthesis and First Evaluation of New 18F-Labelled Sulfonylureas for the Determination of the Beta-Cell Status In Vivo

The syntheses and first in vitro evaluations for two fluoride bearing sulfonylurea derivatives are reported. Firstly, the tolbutamide derivative 1-[4-(2-[18F]fluoroethoxy)benzenesulfonyl]-3-butyl urea (2-[18F]fluoroethyltolbutamide) could be labeled efficiently with [18F]fluoride. Subsequently, the glibenclamid derivative N-(2-(4-(N-((cyclohexylamino)carbonyl)sulfonylamino)phenyl)ethyl) 2-(5-chloro-2-[18F]fluoroethoxy)phenyl formamide (2-[18F]fluoroethyl-glibenclamide) was labeled with [18F]fluoride in high yields. Its ability to induce insuline secretion from rat beta-cells in relation to the original glibenclamide was determined.