69739-21-5

Basic information

• Product Name: (2R,4R)-N-acetyl-2-phenyl-4-carboxy-1,3-thiazolidine
• Synonyms: (2R,4R)-N-acetyl-2-phenyl-4-carboxy-1,3-thiazolidine
• CAS NO: 69739-21-5
• Molecular Weight: 251.306
• Mol File: 69739-21-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (2R,4R)-N-acetyl-2-phenyl-4-carboxy-1,3-thiazolidine(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,4R)-N-acetyl-2-phenyl-4-carboxy-1,3-thiazolidine(69739-21-5)
• EPA Substance Registry System: (2R,4R)-N-acetyl-2-phenyl-4-carboxy-1,3-thiazolidine(69739-21-5)

Safety Data

• Hazardous Substances Data: 69739-21-5(Hazardous Substances Data)

Upstream product

• 100-52-7 benzaldehyde 
• 196930-46-8 (4R)-2-phenyl-1,3-thiazolidine-4-carboxylic acid 
• 108-24-7 acetic anhydride 
• 52-90-4 L-Cysteine 
• 64970-78-1 (2R,4R)-2-phenyl-1,3-thiazolidine-4-carboxylic acid 

Downstream Products

• 72286-35-2 N-((5R)-7-methyl-2ξ-phenyl-4,5-dihydro-[1,3,6]oxathiazepine-5r-carbonyl)-glycine ethyl ester 
• 69739-26-0 (4R)-3-acetyl-2c-phenyl-thiazolidine-4r-carboxylic acid methyl ester 
• 72286-39-6 N-(3-acetyl-2-phenyl-thiazolidine-4-carbonyl)-glycine ethyl ester 

Relevant articles and documents

Synthesis and biological evaluation of new naphthoquinone-containing pyrrolo-thiazoles as anticancer agents

(Chemical Equation Presented) Naphthoquinones undergo 1,3-dipolar cycloaddition with bicyclic muenchnones generated from thiazolidines affording new pyrrolo-thiazoles with a fused quinone nucleus. The products were obtained as single enantiomers in good yields. These benzo[f]thiazolo[4,3-a] isoindole-6,11(1H,3H)-diones are comprised of four fused rings and present a very planar structure. The evaluation of their anticancer activity against melanoma A375 and colorectal adenocarcinoma WiDr human cell lines showed only moderate activity but gave insight into the modeling of new structures. [Color figure can be viewed in the online issue, which is available at www.interscience.wiley.com.]

KAPPA-OPIOID RECEPTOR AGONIST COMPRISING 2-PHENYLBENZOTHIAZOLINE DERIVATIVE

The present invention provides κ opioid receptor agonists comprising 2-phenylbenzothiazoline derivatives. The present invention relates to κ opioid receptor agonists comprising compounds or salts thereof having the chemical structure represented by the ge