6974-65-8

Basic information

• Product Name: 3-(2,4-dichlorophenyl)prop-2-ynoic acid
• Synonyms: 2-propynoic acid, 3-(2,4-dichlorophenyl)-
• CAS NO: 6974-65-8
• Molecular Formula: C₉H₄Cl₂O₂
• Molecular Weight: 215.0329
• Mol File: 6974-65-8.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 364°C at 760 mmHg
• Flash Point: 173.9°C
• Density: 1.53g/cm³
• Vapor Pressure: 6.17E-06mmHg at 25°C
• Refractive Index: 1.634
• CAS DataBase Reference: 3-(2,4-dichlorophenyl)prop-2-ynoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2,4-dichlorophenyl)prop-2-ynoic acid(6974-65-8)
• EPA Substance Registry System: 3-(2,4-dichlorophenyl)prop-2-ynoic acid(6974-65-8)

Safety Data

• Hazardous Substances Data: 6974-65-8(Hazardous Substances Data)

Upstream product

• 42174-01-6 methyl 2,4-dichlorocinnamate 
• 20595-45-3 2,4-dichlorocinnamic acid 
• 24653-94-9 2,3-dibromo-3-(2,4-dichloro-phenyl)-propionic acid 

Downstream Products

• 1417560-52-1 1-(2,4-dichlorophenyl)-2-phenylethane-1,2-dione 
• 1616398-64-1 2-(4-aminophenyl)-6-(2,4-dichlorophenyl)pyrimidin-4(3H)-one 
• 1616398-62-9 2-cyclopropyl-6-(2,4-dichlorophenyl)pyrimidin-4(3H)-one 
• 1616398-66-3 6-(2,4-dichlorophenyl)-2-(pyridin-4-yl)pyrimidin-4(3H)-one 
• 1616398-60-7 6-(2,4-dichlorophenyl)-2-phenylpyrimidin-4(3H)-one 

Relevant articles and documents

Synthesis and antibacterial evaluation of novel 11-O-aralkylcarbamoyl-3-O-descladinosylclarithromycin derivatives

A series of novel 11-O-aralkylcarbamoyl-3-O-descladinosylclarithromycin derivatives were designed, synthesized and evaluated for their in vitro antibacterial activity. The results showed that the majority of the target compounds displayed potent activity against erythromycin-susceptible S. pyogenes, erythromycin-resistant S. pneumoniae A22072 expressing the mef gene and S. pneumoniae AB11 expressing the mef and erm genes. Besides, most of the target compounds exhibited moderate activity against erythromycin-susceptible S. aureus ATCC25923 and B. subtilis ATCC9372. In particular, compounds 11a, 11b, 11c, 11e, 11f and 11h were found to exert favorable antibacterial activity against erythromycin-susceptible S. pyogenes with the MIC values of 0.015–0.125 μg/mL. Furthermore, compounds 10e, 11a, 11b and 11c showed superior activity against erythromycin-resistant S. pneumoniae A22072 with the MIC values of 0.25–0.5 μg/mL. Additionally, compound 11c was the most effective against all the erythromycin-resistant S. pneumoniae strains (A22072, B1 and AB11), exhibiting 8-, 8- and 32-fold more potent activity than clarithromycin, respectively.

Base precursor for heat-developable photosensitive material

A base precursor for heat-developable photosensitive material is disclosed. The precursor is comprised of a compound represented by general formula (I) or (II): The substituents within the general formulae are defined within the specification. The use of this novel base precursor makes it possible to obtain a material which is very stable at normal temperatures and which smoothly decomposes under heating at 80° C. or higher in order to release a basic constituent.