6976-04-1Relevant articles and documents
Preparation method of p-aminobenzene-beta-hydroxyethylsulfone sulfate
-
Paragraph 0079-0081, (2018/01/14)
The invention provides a preparation method of p-aminobenzene-beta-hydroxyethylsulfone sulfate. In the preparation method, parachloronitrobenzene is used as a raw material, and is subjected to reaction steps of reduction, condensation, acylation, catalytic oxidation, esterification and the like, and therefore, the p-aminobenzene-beta-hydroxyethylsulfone sulfate which is high in yield and high in quality can be prepared.
PROCESS FOR PREPARATION OF THIOPHENOL DERIVATIVES
-
Page/Page column 8-9, (2008/06/13)
Provided is a process for preparing thiophenol derivatives, using aromatic disulfide as a starting material, and inexpensive sodium bisulfite (NaHSO3) as a reducing agent. The process can be carried out on an industrial scale at low production costs, secures advantageous reaction conditions by using a small amount of water- soluble alcohol solvent. Further, the process can maximize the purity of the products by inhibiting reverse oxidation of the final product by the action of sulfur dioxide (SO2) produced during the preparation process, after solvent extraction of the starting materials present as impurities of the thiophenol derivatives.