69762-85-2

Basic information

• Product Name: N-(6-AMINOHEXYL)-5-CHLORO-2-NAPHTHALENESULFONAMIDE HYDROCHLORIDE
• Synonyms: OMEGA-9 HYDROCHLORIDE;N-(6-AMINOHEXYL)-5-CHLORO-2-NAPHTHALENESULFONAMIDE HCL;N-(6-AMINOHEXYL)-5-CHLORO-2-NAPHTHALENESULFONAMIDE HYDROCHLORIDE;N-(6-AMINOHEXYL)-5-CHLORO-2-NAPHTHALENESULPHONAMIDE HYDROCHLORIDE;W-7 ISOMER HYDROCHLORIDE;N-(6-aminohexyl)-5-chloro-2-*naphthalenesulfonami;N-(6-AMINOHEXYL)-5-CHLORO-2-NAPHTHALENES ULFONAMIDE
• CAS NO: 69762-85-2
• Molecular Formula: C16H22Cl2N2O2S
• Molecular Weight: 377.33
• Product Categories: All Inhibitors;Inhibitors;Protein Kinase Inhibitors and Activators;Calcium signaling;Aromatics;Sulfur & Selenium Compounds
• Mol File: 69762-85-2.mol
• Article Data: 0

Chemical Properties

• Melting Point: 221-223°C
• Boiling Point: 518.8 °C at 760 mmHg
• Flash Point: 267.6 °C
• Appearance: off-white solid
• Vapor Pressure: 7.24E-11mmHg at 25°C
• Storage Temp.: 2-8°C
• Solubility: DMSO (Slightly), Methanol (Very Slightly, Heated)
• CAS DataBase Reference: N-(6-AMINOHEXYL)-5-CHLORO-2-NAPHTHALENESULFONAMIDE HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N-(6-AMINOHEXYL)-5-CHLORO-2-NAPHTHALENESULFONAMIDE HYDROCHLORIDE(69762-85-2)
• EPA Substance Registry System: N-(6-AMINOHEXYL)-5-CHLORO-2-NAPHTHALENESULFONAMIDE HYDROCHLORIDE(69762-85-2)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 69762-85-2(Hazardous Substances Data)

Usage

Description

N-(6-AMINOHEXYL)-5-CHLORO-2-NAPHTHALENESULFONAMIDE HYDROCHLORIDE is a chemical compound with the potential to act as a calmodulin antagonist. It is characterized by its off-white solid appearance and its ability to bind to calmodulin, which subsequently inhibits the activities of Ca2+/calmodulin-regulated enzymes.

Uses

Used in Pharmaceutical Applications:
N-(6-AMINOHEXYL)-5-CHLORO-2-NAPHTHALENESULFONAMIDE HYDROCHLORIDE is used as a calmodulin antagonist for its ability to inhibit Ca2+/calmodulin-regulated enzyme activities. This property makes it a valuable compound in the development of drugs targeting various diseases and conditions where calmodulin plays a significant role.
Used in Research and Development:
In the field of research, N-(6-AMINOHEXYL)-5-CHLORO-2-NAPHTHALENESULFONAMIDE HYDROCHLORIDE serves as a crucial tool for studying the role of calmodulin in cellular processes. Its use as a calmodulin antagonist allows researchers to investigate the effects of inhibiting calmodulin's activity on various biological pathways and potential therapeutic targets.
Used in Drug Delivery Systems:
Similar to gallotannin, N-(6-AMINOHEXYL)-5-CHLORO-2-NAPHTHALENESULFONAMIDE HYDROCHLORIDE could potentially be incorporated into drug delivery systems to enhance its bioavailability and therapeutic outcomes. By employing various organic and metallic nanoparticles as carriers, the compound's delivery and efficacy could be improved, making it a more effective treatment option for various conditions.

Biological Activity

Calmodulin antagonist (inhibits calmodulin-activated PDE activity with an IC 50 of 72 μ M).

InChI:InChI=1/C16H21ClN2O2S/c17-16-7-5-6-13-12-14(8-9-15(13)16)22(20,21)19-11-4-2-1-3-10-18/h5-9,12,19H,1-4,10-11,18H2/p+1