69776-17-6

Basic information

• Product Name: 3-hydroxy-5-cholenoylglycine
• Synonyms: 3-hydroxy-5-cholenoylglycine
• CAS NO: 69776-17-6
• Molecular Formula: C26H41 N O4
• Molecular Weight: 0
• Mol File: 69776-17-6.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 632.6°C at 760 mmHg
• Flash Point: 336.4°C
• Appearance: /
• Density: 1.15g/cm³
• Vapor Pressure: 1.16E-18mmHg at 25°C
• Refractive Index: 1.56
• CAS DataBase Reference: 3-hydroxy-5-cholenoylglycine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-hydroxy-5-cholenoylglycine(69776-17-6)
• EPA Substance Registry System: 3-hydroxy-5-cholenoylglycine(69776-17-6)

Safety Data

• Hazardous Substances Data: 69776-17-6(Hazardous Substances Data)

Usage

InChI:InChI=1/C26H41NO4/c1-16(4-9-23(29)27-15-24(30)31)20-7-8-21-19-6-5-17-14-18(28)10-12-25(17,2)22(19)11-13-26(20,21)3/h5,16,18-22,28H,4,6-15H2,1-3H3,(H,27,29)(H,30,31)/t16-,18+,19+,20-,21+,22+,25+,26-/m1/s1

Upstream product

• 5255-17-4 3β-hydroxy-5-cholenoic acid 
• 56-40-6 glycine 
• 95013-40-4 methyl 3β-hydroxy-5-cholen-24-oyl-glycinate 
• 623-33-6 glycine ethyl ester hydrochloride 

Relevant articles and documents

Determination of 3β-hydroxy-5-cholen-24-oic acid and its sulfate in human serum by gas chromatography-mass spectrometry

The glycine conjugate of 3β-hydroxy-5-cholen-24-oic acid and its sulfate labeled with deuterium at the C-2, -4 and -23 positions were synthesized.A highly sensitive and specific quantitative assay of the bile acid has been developed by selected ion monitoring in gas chromatography-mass spectrometry of the methyl ester trimethylsilyl ether derivatives using the deuterium labeled conjugates as internal standards.Calibration curves for the bile acid and its sulfate exhibited a linear relationship over the range of 0.01-100 μg/ml in human serum.

Preparation and antigenic properties of methyl 3β-hydroxy-19-oxo-5-cholen-24-oyl-glycinate 19-(O-carboxymethyl)oxime-bovine serum albumin conjugate

The preparation and antigenic properties of 3β-hydroxy-5-cholen-24-oyl-glycine-bovine serum albumin (BSA) conjugate in which the hapten is linked to the carrier protein through an (O-carboxymethyl)oxime bridge at the C-19 position on the steroid portion are described. Antibody raised against the antigen in rabbits possessed high titer and specificity to 3β-hydroxy-5-cholen-24-oyl-glycine, exhibiting no significant cross-reactions with various bile acids.