69829-46-5

Basic information

• Product Name: 7-HYDROXY-2,2-DIPHENYL-BENZO[1,3]DIOXOLE-5-CARBOXYLIC ACID METHYL ESTER
• Synonyms: 7-HYDROXY-2,2-DIPHENYL-BENZO[1,3]DIOXOLE-5-CARBOXYLIC ACID METHYL ESTER
• CAS NO: 69829-46-5
• Molecular Formula: C₂₁H₁₆O₅
• Molecular Weight: 348.35
• Mol File: 69829-46-5.mol
• Article Data: 12

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 7-HYDROXY-2,2-DIPHENYL-BENZO[1,3]DIOXOLE-5-CARBOXYLIC ACID METHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 7-HYDROXY-2,2-DIPHENYL-BENZO[1,3]DIOXOLE-5-CARBOXYLIC ACID METHYL ESTER(69829-46-5)
• EPA Substance Registry System: 7-HYDROXY-2,2-DIPHENYL-BENZO[1,3]DIOXOLE-5-CARBOXYLIC ACID METHYL ESTER(69829-46-5)

Safety Data

• Hazardous Substances Data: 69829-46-5(Hazardous Substances Data)

Upstream product

• 2051-90-3 Dichlorodiphenylmethane 
• 149-91-7 3,4,5-trihydroxybenzoic acid 
• 99-24-1 methyl galloate 

Downstream Products

• 115918-31-5 7-(6-carboxy-2,3,4-trimethoxy-phenoxy)-2,2-diphenyl-benzo[1,3]dioxole-5-carboxylic acid 
• 249610-55-7 methyl 7-(3-(6-(methoxycarbonyl)-2,2-diphenylbenzo[d]-1,3-dioxol-4-yloxy)propoxy)-2,2-diphenylbenzo[d]-1,3-dioxole-5-carboxylate 
• 103162-71-6 methyl 7-(benzyloxy)-2,2-diphenylbenzo[d][1,3]dioxole-5-carboxylate 
• 1192261-82-7 methyl 4,5-dihydroxy-4-methoxy-3-oxo-4,5-O-diphenylmethylidenecyclohexa-1,5-dienecarboxylate 
• 111500-64-2 3,4-diacetoxy-5-benzyloxy-benzoic acid methyl ester 
• 79831-86-0 methyl 3-(benzyloxy)-4,5-dihydroxybenzoate 
• 500359-72-8 2-acetoxy-1-(7-methoxy-2,2-diphenyl-benzo[1,3]dioxol-5-yl)-ethanone 
• 860572-45-8 2-diazo-1-(7-methoxy-2,2-diphenyl-benzo[1,3]dioxol-5-yl)-ethanone 
• 2989-08-4 1-(3,4-diacetoxy-5-methoxy-phenyl)-2-diazo-ethanone 
• 160712-85-6 3,4-diacetoxy-5-methoxy-benzoic acid 

Relevant articles and documents

Polytopic carriers for platinum ions: From digalloyl depside to tannic acid

A novel dinuclear platinum(ii) complex, namely [Pt2m-GG(Me2SO-S)4] (8, GG = deprotonated methyl digallate), was easily synthesized under solvent-free conditions by grinding a solid m/p digalloyl depside with the Pt precursor [PtCO3(Me2SO-S)2]. Similarly, platinum nuclei were introduced into the galloyl chains of tannic acid (TA). In particular, three complexes A, B and C were prepared by reacting TA as a polytopic ligand with an increasing amount of [PtCO3(Me2SO-S)2]. The antiproliferative activity of complexes 8, A, B and C together with the corresponding ligands GG and TA was tested in vitro and compared with that of cisplatin on two human tumor cell lines, A2780 (ovarian cisplatin-sensitive) and A2780cis (ovarian cisplatin-resistant), and one non-tumoral cell line, HaCat. The experiments focusing on their pro-apoptotic activity indicated that the antiproliferative activity of the most active Pt(II) complexes is associated with the induction of apoptosis. This journal is

Inhibitor for FcεRI expression on mast cell from Verbasucum thapsus L.

We found out 2′,3′-dihydroxypuberulin from South American medicinal plant, V. thapsus L., as a candidate of an anti-allergic lead which inhibits the expression of high-affinity receptor of IgE (FcεRI) on the surface of mast cells. Furthermore, the analysis of structure-activity relationship by using synthesized 2′,3′-dihydroxypuberulin analogs revealed that both hydroxy groups in the side chain and both of methyl moieties on phenolic hydroxy groups were crucial for potent activity, but absolute configuration of C-3′ position wasn't. The active principle, 2′,3′-dihydroxypuberulin, was disclosed to down-regulate the mRNA level of β-chain of FcεRI, different from previous reported active natural product reducing γ-chain level.

Isolation, synthesis, and neurite outgrowth-promoting activity of illicinin A from the flowers of Illicium anisatum

Two new prenylated C6-C3 compounds, illicinin A (1) and (4S)-illicinone I (2), were isolated from the flowers of Illicium anisatum. The structures of the new compounds were elucidated by spectroscopic methods. The absolute structure of (4S)-illicinone I was determined by comparing its CD spectrum and specific rotation with those of (4S)-illicinone A (4). Illicinin A (1) and 4-allyl-2,6-dimethoxy-3-(3-methylbut-2-enyl)phenol (3) were found to exhibit neurite outgrowth-promoting activity at concentrations ranging from 0.1 to 10 μM in primary cultured rat cortical neurons. Illicinin A and its derivatives were synthesized for structure-activity relationship studies by employing sequential Stille reactions to introduce a prenyl and an allyl group to the benzene ring, thereby indicating that an allylphenyl moiety in the molecule of 1 is essential for its neurotrophic properties.