699-55-8

Basic information

• Product Name: bicyclo[2.2.2]octane-1-carboxylic acid
• Synonyms: bicyclo[2.2.2]octane-1-carboxylic acid;bicyclo[2.2.2]octane-4-carboxylic acid
• CAS NO: 699-55-8
• Molecular Formula: C₉H₁₄O₂
• Molecular Weight: 154.21
• Mol File: 699-55-8.mol
• Article Data: 7

Chemical Properties

• Melting Point: 140.8-141.3 °C
• Boiling Point: 274.3°Cat760mmHg
• Flash Point: 127.1°C
• Appearance: /
• Density: 1.186g/cm³
• Vapor Pressure: 0.0015mmHg at 25°C
• Refractive Index: 1.542
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 5.07±0.10(Predicted)
• CAS DataBase Reference: bicyclo[2.2.2]octane-1-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: bicyclo[2.2.2]octane-1-carboxylic acid(699-55-8)
• EPA Substance Registry System: bicyclo[2.2.2]octane-1-carboxylic acid(699-55-8)

Safety Data

• Hazardous Substances Data: 699-55-8(Hazardous Substances Data)

Usage

General Description

Bicyclo[2.2.2]octane-1-carboxylic acid is a chemical compound with a unique three-dimensional structure, characterized by a bicyclic framework consisting of three fused cycloalkane rings. It is a carboxylic acid, meaning it contains a functional group consisting of a carboxyl group which consists of a carbon atom double-bonded to an oxygen atom and single-bonded to a hydroxyl group. bicyclo[2.2.2]octane-1-carboxylic acid has limited commercial use, and is primarily used in research and development. Its unique structure and properties make it of interest to chemists and researchers studying the synthesis and properties of organic compounds with complex three-dimensional structures.

InChI:InChI=1/C9H14O2/c10-8(11)9-4-1-7(2-5-9)3-6-9/h7H,1-6H2,(H,10,11)

Upstream product

• 31818-12-9 ethyl bicyclo[2.2.2]octane-1-carboxylate 
• 64-18-6 formic acid 
• 2064-02-0 1-(Hydroxymethyl)bicyclo<2.2.1>heptane 
• 2534-81-8 Methyl-bicyclo<2.2.2>oct-2-en-1-carboxylat 
• 18720-35-9 bicyclo[2.2.2]octane-1,4-dicarboxylic acid monomethyl ester 
• 30810-15-2 methyl cyclohexa-1,3-diene-1-carboxylate 
• 3048-85-9 1-Aethoxycarbonyl-bicyclo<2.2.2>octan-2,3-dicarbonsaeure 
• 3037-84-1 ethyl bicyclo[2.2.2]oct-2-ene-1-carboxylate 
• 15023-45-7 methyl exo-2-bromobicyclo<2.2.1>heptane-1-carboxylate 
• 2534-90-9 exo-2-bromobicyclo<2.2.1>heptane-1-carboxylic acid 
• 85173-54-2 exo-2-bromobicyclo<2.2.1>heptane-1-carboxylic acid chloride 
• 18720-30-4 norbornane-1-carboxylic acid 
• 2287-57-2 methyl bicyclo<2.2.1>heptane-1-carboxylate 
• 2574-42-7 bicyclo<2.2.2>octane-1-methanol 

Downstream Products

• 1193-42-6 1-aminobicyclo<2.2.2>octane 
• 25344-96-1 oct-1-yl-methyl>-amin 
• 7363-97-5 bicyclo<2.2.2>octane-1-carboxaldehyde tosylhydrazone 
• 149891-94-1 bicyclo<2.2.2>octane-1-carboxaldehyde-d tosylhydrazone 
• 96454-73-8 bicyclo<2.2.2>octylacetylene 
• 931-98-6 1-bicyclo<2.2.2>octyliodide 
• 79635-09-9 N-Benzylbicyclo<2.2.2>octan-1-carboxamid 
• 90978-21-5 N-octyl-(1)>-carbaminsaeure-methylester 
• 280-33-1 bicyclo[2,2,2]octane 
• 131230-08-5 anti-1-Bicyclo<2.2.2>octylmethylketoxim-pikrat 
• 931-98-6 1-Iodobicyclo<2.2.2>octane 
• 2574-42-7 bicyclo<2.2.2>octane-1-methanol 

Relevant articles and documents

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MITOCHONDRIA-TARGETING PEPTIDES

Disclosed are analogs of SBT-20. The compounds are useful for the treatment and prevention of ischemia-reperfusion injury (e.g., cardiac ischemia-reperfusion injury) or myocardial infarction.

Oxoammonium salts. 6. 4-Acetylamino-2,2,6,6-tetramethylpiperidine-1- oxoammonium perchlorate: A stable and convenient reagent for the oxidation of alcohols. Silica gel catalysis

4-Acetylamino-2,2,6,6-tetramethylpiperidine-1-oxoammonium perchlorate, 1, is a stable, nonhygroscopic oxoammonium salt that is easily prepared and can be used for the oxidation of alcohols to ketones or aldehydes in near quantitative yields. The reaction is colorimetric, does not require anhydrous conditions, does not involve heavy metals, and can be carried out conveniently. Furthermore, the oxidant can be easily regenerated. The oxidation is somewhat specific in that the relative reactivities of an allyl alcohol (geraniol), benzaldehyde, and 1-decanol are about 100:1:0.1. The reaction is catalyzed by silica gel.

Decarboxylation of Bridgehead Carboxylic Acids by the Barton Procedure

Reductive decarboxylation of a series of bicyclic and polycyclic acids in which the carboxyl group is attached to the bridgehead position has been investigated.Conversion of the acids into thiohydroxamic esters occurs via reaction of the derived acid chlorides with N-hydroxypyridine-2-thione.Decomposition of the esters proceeds smoothly in boiling benzene in the presence of 1-butyl mercaptan to give the reduced product in high yield.The procedure appears to be generally applicable, and is unaffected by functional groups such as esters and acetals.