69981-34-6

Basic information

• Product Name: (R)-2-amino-N-tert-butyl-3-methylbutanamide
• Synonyms: (R)-2-amino-N-tert-butyl-3-methylbutanamide;(2R)-2-Amino-N-(1,1-dimethylethyl)-3-methylbutanamide
• CAS NO: 69981-34-6
• Molecular Formula: C₉H₂₀N₂O
• Molecular Weight: 172.27
• Mol File: 69981-34-6.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• Density: 0.918
• CAS DataBase Reference: (R)-2-amino-N-tert-butyl-3-methylbutanamide(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-2-amino-N-tert-butyl-3-methylbutanamide(69981-34-6)
• EPA Substance Registry System: (R)-2-amino-N-tert-butyl-3-methylbutanamide(69981-34-6)

Safety Data

• Hazardous Substances Data: 69981-34-6(Hazardous Substances Data)

Usage

Description

(R)-2-amino-N-tert-butyl-3-methylbutanamide is an organic amide with the molecular formula C10H22N2O. It is composed of an amino group and a tert-butyl group attached to a methylbutanamide chain.

Uses

Used in Pharmaceutical Industry:
(R)-2-amino-N-tert-butyl-3-methylbutanamide is used as a building block for the synthesis of various drugs and pharmaceuticals due to its unique chemical structure and properties.
Used in Research Laboratories:
(R)-2-amino-N-tert-butyl-3-methylbutanamide is used as a reagent in chemical reactions and as a reference standard for analytical testing, contributing to the advancement of scientific research and development.

Upstream product

• 1149-26-4 (S)-N-(benzyloxycarbonyl)valine 
• 61274-17-7 N-carbobenzoxy-L-valyl-tert-butylamide 
• 86154-20-3 (S)-tert-butyl 1-(tert-butylamino)-3-methyl-1-oxobutan-2-ylcarbamate 
• 13734-41-3 t-Boc-L-valine 
• 70421-65-7 L-valine tert-butylamide hydrochloride 
• 72-18-4 L-valine 
• 5511-73-9 N-phthalimide l-valinyl chloride 
• 178421-57-3 (S)-N-tert-Butyl-2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-3-methyl-butyramide 
• 6306-54-3 N-phthaloyl L-valine 

Downstream Products

• 161510-58-3 SDZ 282314 
• 890022-49-8 {(R)-1-Benzyl-3-[(S)-2-((S)-1-tert-butylcarbamoyl-2-methyl-propylcarbamoyl)-pyrrolidin-1-yl]-1-[1,3]dithiolan-2-yl-propyl}-carbamic acid allyl ester 
• 1375257-36-5 (S)-1-tert-butyl-3-[(R)-3-hydroxy-3-phenylpropanoyl]-4-isopropylimidazolidin-2-one 

Relevant articles and documents

Electrostatic repulsion and hydrogen-bonding interactions in a simple N-aryl-L-valinamide organocatalyst control the stereoselectivity in asymmetric aldol reactions

A novel stereocontrol method for asymmetric aldol reactions of aldehydes with ketones is described. The stereoselectivity of the products is controlled by the electrostatic repulsion and hydrogen-bonding interactions of an N-aryl-L-valinamide catalyst. Th

Chiral calcium catalysts for asymmetric hydroamination/cyclisation

Calcium complexes supported by chiral 1,2-diamines have been shown to be efficient catalysts for the asymmetric hydroamination of amino-olefin substrates; the calcium complexes [Ca(NNR){N(SiMe3) 2}(THF)] (R = tBu, iPr, Ph, 4-C 6H4F) give enantioselectivities of up to 26% which marks a significant increase based upon literature precedence. The structure of [Ca(NNPh){N(SiMe3)2}(py)] has been computed with density functional methods.

Synthesis of an enantiomerically pure resorcinarene with pendant L-valine residues and its attachment to a polysiloxane (Chirasil-Calix)

The synthesis of a new enantiomerically pure resorcinarene by reaction of all resorcinic groups with N-bromoacetyl-L-valine-tert-butyl-amide is described. The chiral macrocyclic product was chemically bonded to a poly(hydro)dimethylsiloxane by hydrosilylation using a platinum catalyst. The resulting chiral polysiloxane Chirasil-Calix can be used as chiral stationary phase (CSP) in capillary gas chromatography.