700-91-4 Usage
Description
5-PHENYL-3,4-DIHYDRO-2H-PYRROLE is a heterocyclic chemical compound with the molecular formula C10H11N. It features a pyrrole ring fused with a phenyl group, making it a colorless liquid at room temperature. 5-PHENYL-3,4-DIHYDRO-2H-PYRROLE is known for its unique structure and reactivity, which contribute to its diverse applications in organic chemistry, pharmaceuticals, and agrochemicals.
Uses
Used in Pharmaceutical Synthesis:
5-PHENYL-3,4-DIHYDRO-2H-PYRROLE is utilized as a key intermediate in the synthesis of various pharmaceuticals. Its unique structure allows it to be a building block for the development of new drugs with potential therapeutic applications.
Used in Agrochemical Synthesis:
In the agrochemical industry, 5-PHENYL-3,4-DIHYDRO-2H-PYRROLE is employed as a precursor for the production of various agrochemicals. Its incorporation into these products can enhance their effectiveness in agricultural applications.
Used in Drug Development:
5-PHENYL-3,4-DIHYDRO-2H-PYRROLE has been studied for its potential pharmacological activities, such as its role as a dopamine receptor antagonist. This makes it a promising candidate for the development of drugs targeting neurological disorders and other conditions related to dopamine dysregulation.
Used in Material Science:
Due to its unique structure and reactivity, 5-phenyl-3,4-dihydro-2H-pyrrole has been investigated for its potential use in the development of new materials and functional molecules. Its properties may contribute to the creation of innovative materials with specific applications in various industries.
Overall, 5-PHENYL-3,4-DIHYDRO-2H-PYRROLE is a versatile compound with applications spanning across pharmaceuticals, agrochemicals, drug development, and material science, making it an important component in the advancement of various fields.
Check Digit Verification of cas no
The CAS Registry Mumber 700-91-4 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 7,0 and 0 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 700-91:
(5*7)+(4*0)+(3*0)+(2*9)+(1*1)=54
54 % 10 = 4
So 700-91-4 is a valid CAS Registry Number.
InChI:InChI=1/C9H10N2/c1-2-9(11-5-1)8-3-6-10-7-4-8/h3-4,6-7H,1-2,5H2
700-91-4Relevant articles and documents
Novel Kumada coupling reaction to access cyclic (2-azaallyl)stannanes. Cycloadditions of cyclic nonstabilized 2-azaallyllithium species derived from cyclic (2-azaallyl)stannanes
Mans, Douglas M.,Pearson, William H.
, p. 6419 - 6426 (2004)
A Kumada cross-coupling reaction involving organomagnesium reagents and (3-methylthio-2-azaallyl)stannanes with a Ni(O) catalyst provided cyclic nonstabilized (2-azaallyl)stannanes in moderate to good yields. Primary alkyl, aryl, and allylic organomagnesi
Domino Synthesis of 4-Alkylidene-3,4-dihydro-2H-pyrroles from Homopropargyl Sulfonamides and Aldehydes
Amemiya, Sho,Takahashi, Yui,Tsubouchi, Akira,Saito, Akio
supporting information, p. 5717 - 5724 (2021/10/30)
Abstract: We describe a domino synthesis of 4-alkylidene-3,4-dihydro-2H-pyrroles from aryl-substituted homopropargyl sulfonamides and aldehydes promoted by cheap and easy-to-handle TsOH ? H2O. The present reactions proceed through cyclocondensation of α-sulfonamidoethyl-α,β-enone intermediates, which are formed by ring-cleavage of 3-acylpyrrolidines corresponding to aza-Prins cyclized intermediates. By controlling the conditions, 3-acylpyrrolidines can be obtained.
Iron(II)-Catalyzed Aerobic Biomimetic Oxidation of Amines using a Hybrid Hydroquinone/Cobalt Catalyst as Electron Transfer Mediator
Guemundsson, Arnar,Manna, Srimanta,B?ckvall, Jan-E.
supporting information, p. 11819 - 11823 (2021/04/29)
Herein we report the first FeII-catalyzed aerobic biomimetic oxidation of amines. This oxidation reaction involves several electron transfer steps and is inspired by biological oxidation in the respiratory chain. The electron transfer from the amine to molecular oxygen is aided by two coupled catalytic redox systems, which lower the energy barrier and improve the selectivity of the oxidation reaction. An iron hydrogen transfer complex was utilized as the substrate-selective dehydrogenation catalyst along with a bifunctional hydroquinone/cobalt Schiff base complex as a hybrid electron transfer mediator. Various primary and secondary amines were oxidized in air to their corresponding aldimines or ketimines in good to excellent yield.