701-14-4

Basic information

• Product Name: 1H-Benzimidazol-2-amine,4-chloro-(9CI)
• Synonyms: 1H-Benzimidazol-2-amine,4-chloro-(9CI);7-chloro-1H-benzo[d]iMidazol-2-aMine;2-AMine-7-chloro-1H-benziMidazol;4-Chloro-1H-benzo[d]iMidazol-2-aMine;4-Chloro-1H-benzimidazol-2-amine;7-Chloro-1H-benzimidazol-2-amine;2-Amino-4-chloro-1H-benzimidazole;2-Amino-7-chloro-1H-benzimidazole
• CAS NO: 701-14-4
• Molecular Formula: C7H6ClN3
• Molecular Weight: 167.59564
• Product Categories: BENZIMIDAZOLE
• Mol File: 701-14-4.mol
• Article Data: 3

Chemical Properties

• Melting Point: 197-199℃
• Boiling Point: 402.5±37.0 °C(Predicted)
• Appearance: /
• Density: 1.533±0.06 g/cm3(Predicted)
• PKA: 9.01±0.30(Predicted)
• CAS DataBase Reference: 1H-Benzimidazol-2-amine,4-chloro-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Benzimidazol-2-amine,4-chloro-(9CI)(701-14-4)
• EPA Substance Registry System: 1H-Benzimidazol-2-amine,4-chloro-(9CI)(701-14-4)

Safety Data

• Hazard Codes: Xn
• Statements: 22-36/37/38
• Safety Statements: 26
• WGK Germany: 3
• Hazardous Substances Data: 701-14-4(Hazardous Substances Data)

Usage

General Description

1H-Benzimidazol-2-amine,4-chloro-(9CI) is a chemical compound with the molecular formula C7H6ClN3. It is a derivative of benzimidazole, a heterocyclic aromatic organic compound. This chemical is a type of benzimidazole amine that contains a chlorine atom at the 4-position of the benzimidazole ring. It may have potential applications in various fields such as pharmaceuticals, agrochemicals, and material science. The specific properties and uses of this compound would depend on further research and development.

Upstream product

• 506-68-3 bromocyane 
• 21745-41-5 2,3-diaminochlorobenzene 

Relevant articles and documents

JAK-2 MODULATORS AND METHODS OF USE

This invention relates to the field of protein tyrosine kinases and inhibitors thereof. In particular, the invention relates to inhibitors of JAK-2, pharmaceutical compositions of the compounds for inhibiting JAK-2, methods of inhibiting JAK-2 in a cell, comprising contacting a cell in which inhibition of JAK-2 is desired with a compound or pharmaceutical composition comprising a compound according to the invention. The also comprises methods of treating a disease or condition that involves JAK-2 comprising administering to a patient a pharmaceutical composition comprising a compound according to the invention

Iminoisoindolinone metal complex

Iminoisoindolinone metal complexes of formula STR1 wherein A represents a 5- or 6-membered heterocyclic radical which contains at least one further heteroatom and can be fused or doubled with benzene nuclei, M represents a divalent metal atom excluding the alkaline earth metals, X represents a hydrogen atom, Y represents a halogen atom, Z represents a nitro group, an alkoxycarbonyl group of 2 to 6 carbon atoms or a group of formula RY2 --, wherein R represents a hydrogen atom, an alkyl group of 1 to 6 carbon atoms which is substituted by an aryl radical or is unsubstituted, a cycloalkyl group of 5 to 6 carbon atoms, or represents an aryl group, and Y2 represents an oxygen or a sulphur atom, m and n are 0 to 4, p is 0 to 2, and the sum of m+n+p must be 4, which are useful for pigmenting high molecular organic material.