701198-67-6Relevant articles and documents
Novel 1-hydroxyazole bioisosteres of glutamic acid. Synthesis, protolytic properties, and pharmacology
Stensb?l,Uhlmann,Morel,Eriksen,Felding,Kromann,Hermit,Greenwood,Braüner-Osborne,Madsen,Junager,Krogsgaard-Larsen,Begtrup,Veds?
, p. 19 - 31 (2007/10/03)
A number of 1-hydroxyazole derivatives were synthesized as bioisosteres of (S)-glutamic acid (Glu) and as analogues of the AMPA receptor agonist (R,S)-2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic acid (AMPA, 3b). All compounds were subjected to in
