70144-18-2 Usage
Description
(-)-(2R,5R)-2,5-DIMETHYLPYRROLIDINE, HYDROCHLORIDE is a white crystalline solid that is utilized as a reagent in the field of asymmetric syntheses. It is a chiral compound with specific stereochemistry, which makes it valuable for creating enantiomerically pure products in chemical reactions.
Uses
Used in Pharmaceutical Industry:
(-)-(2R,5R)-2,5-DIMETHYLPYRROLIDINE, HYDROCHLORIDE is used as a reagent for asymmetric syntheses to produce enantiomerically pure compounds. This is crucial in the pharmaceutical industry, as the desired biological activity and safety profile of many drugs are dependent on their stereochemistry.
Used in Chemical Research:
In the field of chemical research, (-)-(2R,5R)-2,5-DIMETHYLPYRROLIDINE, HYDROCHLORIDE is used as a reagent for asymmetric syntheses to develop novel compounds with potential applications in various industries, including pharmaceuticals, agrochemicals, and materials science.
Used in Material Science:
(-)-(2R,5R)-2,5-DIMETHYLPYRROLIDINE, HYDROCHLORIDE is used as a reagent for asymmetric syntheses to create chiral materials with specific properties. These materials can be employed in various applications, such as sensors, catalysts, and advanced materials with unique optical, electronic, or mechanical properties.
Used in Agrochemical Industry:
(-)-(2R,5R)-2,5-DIMETHYLPYRROLIDINE, HYDROCHLORIDE is used as a reagent for asymmetric syntheses to produce enantiomerically pure active ingredients for agrochemicals. The stereochemistry of these compounds can significantly influence their effectiveness and selectivity in controlling pests and diseases in agriculture.
Check Digit Verification of cas no
The CAS Registry Mumber 70144-18-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,0,1,4 and 4 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 70144-18:
(7*7)+(6*0)+(5*1)+(4*4)+(3*4)+(2*1)+(1*8)=92
92 % 10 = 2
So 70144-18-2 is a valid CAS Registry Number.
70144-18-2Relevant articles and documents
Beta-carbolines useful for treating inflammatory disease
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Page/Page column 109-110, (2010/02/14)
This invention provides beta-carboline compounds of formula III-A-aa: wherein Q, G, R1, R2, R3, and R6b are as described in the specification. The compounds are useful for treating diseases such as inflammatory diseases and cancer.
An evaluation of some hindered diamines as chiral modifiers of metal-promoted reactions
Illesinghe, Jayamini,Ebeling, Richard,Ferguson, Brett,Patel, Jim,Campi, Eva M.,Jackson, W. Roy,Robinson, Andrea J.
, p. 167 - 176 (2007/10/03)
Diamino analogues of the C2-symmetric chiral diphosphine ligands DuPHOS and BPE have been prepared and evaluated as chiral modifiers of the osmium tetraoxide dihydroxylation of stilbene. NMR experiments showed that these ligands were too bulky to coordinate to osmium. Less hindered analogues of these ligands were prepared and some were shown to act as ligands in dihydroxylation reactions but with poor enantioselectivity (e.e. 10%). The diamines have also been briefly evaluated as ligands in rhodium-catalyzed hydroformylation and copper-catalyzed phenolic coupling reactions. Once again, only low enantioselectivity was obtained.
Diastereoselective synthesis of 2,5-dimethylpyrrolidines and 2,6- dimethylpiperidines by reductive amination of 2,5-hexanedione and 2,6- heptanedione with hydride reagents
Boga,Manescalchi,Savoia
, p. 4709 - 4722 (2007/10/02)
The reductive amination of 2,5-hexanedione and 2,6-heptanedione with ammonia and primary amines in the presence of hydride reagents afforded 2,5- dimethylpyrrolidines and 2,6-dimethylpiperidines with variable diastereoselectivity, as the cis/trans ratio was affected by the size of the ring formed and the steric and electronic properties of the nitrogen substituent. Increasing the bulkiness of the nitrogen substituent, the cis pyrrolidines and the trans-piperidines were obtained with enhanced selectivity.
