70253-67-7

Basic information

• Product Name: 6-MB-CAMP SODIUM SALT
• Synonyms: N6-MONOBUTYRYLADENOSINE 3':5'-CYCLIC MONOPHOSPHATE SODIUM SALT;N6-MONOBUTYRYLADENOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT;N6-MONOBUTYRYLADENOSINE 3':5'-CYCLIC*MON OPHOSPHATE;N6-Butyryladenosine-3'',5''-cyclic monophosphoric acid monosodium salt;6MB-cAMP;n6-monobutyryladenosine-3’,5’-cyclicmonophosphate,sodiumsalt(6-mb-camp);ADENOSINE 3',5'-CYCLIC MONOPHOSPHATE, N6-MONOBUTYRYL-, SODIUM SALT;6-MB-CAMP, NA
• CAS NO: 70253-67-7
• Molecular Formula: C14H17N5NaO7P
• Molecular Weight: 421.28
• Product Categories: Biochemicals and Reagents;Nucleosides, Nucleotides, Oligonucleotides;Nucleotide Analogs
• Mol File: 70253-67-7.mol
• Article Data: 0

Chemical Properties

• Boiling Point: Not available.
• Flash Point: Not available.
• Appearance: Crystalline solid.)
• Density: Not available.
• Storage Temp.: −20°C
• Solubility: DMSO (Slightly), Water (Slightly)
• Stability: Hygroscopic
• CAS DataBase Reference: 6-MB-CAMP SODIUM SALT(CAS DataBase Reference)
• NIST Chemistry Reference: 6-MB-CAMP SODIUM SALT(70253-67-7)
• EPA Substance Registry System: 6-MB-CAMP SODIUM SALT(70253-67-7)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 70253-67-7(Hazardous Substances Data)

Usage

Description

6-MB-CAMP SODIUM SALT, also known as N6-Monobutyryladenosine 3′:5′-cyclic monophosphate sodium salt, is a chemical compound that functions as a protein kinase A activator. It plays a crucial role in modulating various biological processes by regulating the cAMP cascade, which is an essential component of cellular signaling pathways.
Used in Neuroscience Research:
6-MB-CAMP SODIUM SALT is used as a research tool for testing the hypothesis that it stimulates the long-lasting potentiation of postganglionic responses. This application helps scientists understand the underlying mechanisms of synaptic plasticity and neuronal communication.
Used in Endocrinology Research:
In human primary cultured thyrocytes, 6-MB-CAMP SODIUM SALT is used as a protein kinase A activator for analyzing the modulations in cAMP cascade regulated gene expression. This research aids in understanding the role of cAMP signaling in thyroid function and related disorders.
Used in Reproductive Biology Research:
6-MB-CAMP SODIUM SALT is used to analyze its effect on progesterone production in the corpus luteum isolated from pseudopregnant rabbits. This application helps researchers investigate the role of cAMP signaling in the regulation of progesterone synthesis and its impact on reproductive health.

Biochem/physiol Actions

Membrane permeable analog of cAMP that activates protein kinase A and is resistant to degradation by phosphodiesterase

InChI:InChI=1/C14H18N5O7P.Na/c1-2-3-8(20)18-12-9-13(16-5-15-12)19(6-17-9)14-10(21)11-7(25-14)4-24-27(22,23)26-11;/h5-7,10-11,14,21H,2-4H2,1H3,(H,22,23)(H,15,16,18,20);