702684-44-4 Usage
General Description
Phenol, 2-[(1S)-1-aminoethyl]-3-methyl- (9CI) is a chemical compound that belongs to the class of phenol derivatives. It is a derivative of phenol with a 1-aminoethyl and 3-methyl group attached to the phenol ring. Phenol, 2-[(1S)-1-aminoethyl]-3-methyl- (9CI) is a chiral molecule with a stereocenter at the 1-position, indicating that it has a specific spatial arrangement of its atoms. It may have potential applications in pharmaceuticals, organic synthesis, or as a building block for other chemical compounds. Its precise function and properties would depend on its specific molecular structure and chemical reactivity.
Check Digit Verification of cas no
The CAS Registry Mumber 702684-44-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,0,2,6,8 and 4 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 702684-44:
(8*7)+(7*0)+(6*2)+(5*6)+(4*8)+(3*4)+(2*4)+(1*4)=154
154 % 10 = 4
So 702684-44-4 is a valid CAS Registry Number.
InChI:InChI=1/C9H13NO/c1-6-4-3-5-8(11)9(6)7(2)10/h3-5,7,11H,10H2,1-2H3/t7-/m0/s1
702684-44-4Relevant articles and documents
Asymmetric Syntheses of 2-(1-Aminoethyl)phenols
Kuendig, E. Peter,Botuha, Candice,Lemercier, Gilles,Romanens, Patrick,Saudan, Lionel,Thibault, Sylvie
, p. 561 - 579 (2007/10/03)
Three different routes were probed for the synthesis of enantiomerically enriched 2-(1-aminoethyl)phenols and their methyl ethers. The first route centers on diastereoselective nucleophile addition to chiral imines. The second route has as key steps the enantioselective reduction of a ketone followed by nucleophilic substitution, and the third route involves a diastereoselective imine reduction. The efficiency of the approach depends on the substrate substitution pattern. All three methods work well for the parent compound 2-(1-aminoethyl)phenol (1) but the third route is the most efficient, providing the compound with >96% enantiomer excess in three steps with an overall yield of 71%. Conversely, for the ortho-methyl analogue 2, the first method is best. For the t-Bu-substituted analogue 3, only moderate enantiomeric enrichment was achieved.