70298-83-8

Basic information

• Product Name: N-(3,4-dimethylphenyl)-2,2-dimethylpropanamide
• Synonyms: N-(3,4-dimethylphenyl)-2,2-dimethylpropanamide
• CAS NO: 70298-83-8
• Molecular Weight: 205.3
• Mol File: 70298-83-8.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: N-(3,4-dimethylphenyl)-2,2-dimethylpropanamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(3,4-dimethylphenyl)-2,2-dimethylpropanamide(70298-83-8)
• EPA Substance Registry System: N-(3,4-dimethylphenyl)-2,2-dimethylpropanamide(70298-83-8)

Safety Data

• Hazardous Substances Data: 70298-83-8(Hazardous Substances Data)

Upstream product

• 1538-75-6 2,2-dimethylpropanoic anhydride 
• 95-64-7 4-amino-o-xylene 
• 3282-30-2 pivaloyl chloride 

Downstream Products

• 107125-89-3 2-bromo-3,4-dimethyl-N-(2,2-dimethylpropanoyl)aniline 
• 107125-88-2 6-bromo-3,4-dimethyl-N-(2,2-dimethylpropanoyl)aniline 
• 107125-91-7 3,4-dimethyl-N-neo-pentylaniline 
• 1433186-71-0 N-(4,5-dimethyl-2-(trifluoromethyl)phenyl)pivalamide 
• 1452922-59-6 methyl 2-(4,5-dimethyl-2-(pivalamido)phenyl)-3-oxo-3-(thiophen-2-yl)propanoate 
• 1452922-58-5 methyl 3-(4-methoxyphenyl)-2-(4,5-dimethyl-2-(pivalamido)phenyl)-3-oxopropanoate 
• 1452922-57-4 methyl 3-(3-(trifluoromethyl)phenyl)-2-(4,5-dimethyl-2-(pivalamido)phenyl)-3-oxopropanoate 
• 1452922-56-3 methyl 3-(4-bromophenyl)-2-(4,5-dimethyl-2-(pivalamido)phenyl)-3-oxopropanoate 
• 1452922-55-2 ethyl 2-(4,5-dimethyl-2-(pivalamido)phenyl)-3-oxo-3-phenylpropanoate 
• 1452922-54-1 ethyl 2-(4,5-dimethyl-2-(pivalamido)phenyl)-3-oxobutanoate 
• 1452922-66-5 benzyl 2-(ethoxymethyl)-5,6-dimethyl-1H-indole-3-carboxylate 
• 1452922-53-0 benzyl 2-(4,5-dimethyl-2-(pivalamido)phenyl)-3-oxobutanoate 
• 1452922-52-9 diethyl 2-(4,5-dimethyl-2-(pivalamido)phenyl)-2-phenylmalonate 
• 1452922-51-8 1-(3-chlorobenzyl) 3-methyl 2-(4,5-dimethyl-2-(pivalamido)phenyl)malonate 

Relevant articles and documents

Equivalent Loading of Directed Arenes in Pd(II)-Catalyzed Oxidative Cross-Coupling of Aryl C-H Bonds at Room Temperature

The unsymmetrical biaryls (Ar1-Ar2) produced by the catalytic cross-couplings of aryl halides (Ar1-halo) with aryl metallics (Ar2-M) in the loading ratio of 1:1 are popular in chemical synthesis. In contrast, there has been less precedence on the same biaryls produced effectively from two normal aryl C-H bonds with equivalent loading. Here, we report that, in a palladium/oxidant/acid catalytic system at room temperature, one arene (Ar1-H, 1 equiv) can highly selectively couple with the other one (Ar2-H, 1 equiv) to afford the target Ar1-Ar2 just by controlling the directing groups and the substituted groups on their phenyl rings. The utility of this one-one cross-coupling is also demonstrated by synthesis of a few bioactive molecules.

Rhodium(III)-catalysed, redox-neutral C(sp2)-H alkenylation using pivalimide as a directing group with internal alkynes

In the presence of [RhCp?Cl2]2, N-pivaloyl anilines react with internal alkynes to give the corresponding 2-alkenylpivalimides under redox neutral conditions through C-H activation. This redox neutral hydroarylation, which does not require an external organic acid, unlocks a regioselective synthetic route to 2-alkenyl anilines and is generally applicable to diversely substituted electron rich and electron poor pivalimides.

A highly efficient Pd-catalyzed decarboxylative ortho-arylation of amides with aryl acylperoxides

An efficient Pd-catalyzed decarboxylative ortho-arylation of amides with aryl acylperoxides was developed. A variety of anilides reacted with aryl acylperoxides to afford the corresponding ortho-arylation products, and N-methoxyarylamides generated phenanthridinones. This journal is