7031-28-9

Basic information

• Product Name: Acetyl chloride, [(phenylmethyl)thio]-
• CAS NO: 7031-28-9
• Molecular Formula: C9H9ClOS
• Molecular Weight: 200.689
• Mol File: 7031-28-9.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: Acetyl chloride, [(phenylmethyl)thio]-(CAS DataBase Reference)
• NIST Chemistry Reference: Acetyl chloride, [(phenylmethyl)thio]-(7031-28-9)
• EPA Substance Registry System: Acetyl chloride, [(phenylmethyl)thio]-(7031-28-9)

Safety Data

• Hazardous Substances Data: 7031-28-9(Hazardous Substances Data)

Upstream product

• 2899-67-4 ethyl (benzylthio)acetate 
• 100-44-7 benzyl chloride 
• 100-39-0 benzyl bromide 
• 103-46-8 S-benzylmercaptoacetic acid 

Downstream Products

• 428496-97-3 2-(Benzylthio)-N-cyclopropylacetamid 
• 51469-63-7 2-(benzylthio)-N,N-dimethylacetamide 
• 87122-90-5 2-Benzylsulfanyl-N-methyl-acetamide 
• 101718-03-0 benzylsulfanyl-acetic acid-((S)-1-methyl-2-phenyl-ethylamide) 
• 3595-28-6 2-benzylsulfanyl-N-((5aR)-1,7-dioxo-(5ar)-1,4,6,7-tetrahydro-3H,5aH-azeto[2,1-b]furo[3,4-d][1,3]thiazin-6t-yl)-acetamide 
• 3595-32-2 (6R)-7t-(2-benzylsulfanyl-acetylamino)-3-carbamimidoylsulfanylmethyl-8-oxo-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 
• 174456-04-3 N-(benzylthio)acetyl-4-chloro-anthranilic acid methyl ester 
• 174455-71-1 7-chloro-3-(benzylsulfinyl)-4-hydroxy-2(1H)-quinolone 

Relevant articles and documents

Synthesis of Cyclic α-Diazo-β-keto Sulfoxides in Batch and Continuous Flow

Diazo transfer to β-keto sulfoxides to form stable isolable α-diazo-β-keto sulfoxides has been achieved for the first time. Both monocyclic and benzofused ketone derived β-keto sulfoxides were successfully explored as substrates for diazo transfer. Use of continuous flow leads to isolation of the desired compounds in enhanced yields relative to standard batch conditions, with short reaction times, increased safety profile, and potential to scale up.

Crystal Structure of 3-(4-Methoxy-benzylidene)-isothiochroman-4-one

The title compound, 3-(4-methoxy-benzylidene)-isothiochroman-4-one (C 17H14O2S) was prepared from the reaction of isothiochroman-4-one with benzaldehyde in the presence of small amount of HCl. The structure of the synthesised compound was determined by IR, 1H NMR and X-ray crystallography. The structure was solved in monoclinic, space group P21/n with a = 3.9773 (7) A, b = 10.918 (2) A, c = 30.609 (6) A, β = 90.615 (3)°, V = 1329.1 (4) A3, Z = 4 and with R int = 0.047. The bicyclic ring of isothiochroman-4-one moiety does not adopt a planar geometry. The molecular conformation is stable via C10-H???O1 and C16- H???S1 intramolecular hydrogen-bonding interactions. These contacts involve molecules in an extended two-dimensional sheet to the bc plane.

SUBSTITUTED CYCLOHEXYL-1,4-DIAMINE DERIVATIVES WITH A CHAIN EXTENSION

The invention relates to substituted cyclohexyl-1,4-diamine derivatives, to a method for their production, to medicaments containing said compounds and to the use of substituted cyclohexyl-1,4-diamine derivatives for producing medicaments.