70375-24-5

Basic information

• Product Name: BOC-VAL-PRO-ARG-AMC HCL
• Synonyms: N-T-BOC-VAL-PRO-ARG 7-AMIDO-4-METHYLCOUMARIN HYDROCHLORIDE;BOC-VAL-PRO-ARG-AMC HCL;BOC-VPR-AMC HCL;N-T-boc-val-pro-arg 7-amido-4-*methylcoumarin hyd;N-T-BOC-VAL-PRO-ARG 7-AMIDO-4-METHYLCOUM ARIN HYDRO;N-t-Boc-Val-Pro-Arg 7-amino-4-methylcoumarin hydrochloride;boc-val-pro-arg-7-amido-4-methylcoumarin hydrochloride;N-tert-Butoxycarbonyl-L-valyl-L-prolyl-L-arginine 7-amido-4-methylcoumarin
• CAS NO: 70375-24-5
• Molecular Formula: C31H46ClN7O7
• Molecular Weight: 664.19
• Product Categories: Coagulation Proteins and ReagentsEnzyme Substrates;Plasma&Blood Proteins;Protease Substrates;Proteins and Derivatives;Substrates by Enzyme;Thrombin;ThrombinEnzyme Substrates
• Mol File: 70375-24-5.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Storage Temp.: −20°C
• CAS DataBase Reference: BOC-VAL-PRO-ARG-AMC HCL(CAS DataBase Reference)
• NIST Chemistry Reference: BOC-VAL-PRO-ARG-AMC HCL(70375-24-5)
• EPA Substance Registry System: BOC-VAL-PRO-ARG-AMC HCL(70375-24-5)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 70375-24-5(Hazardous Substances Data)

Usage

Description

BOC-VAL-PRO-ARG-AMC HCL, also known as Boc-Val-Pro-Arg-7-amido-4-methylcoumarin hydrochloride, is a synthetic peptide compound that serves as a fluorogenic substrate for various assays. It is designed to mimic the natural substrates of proteolytic enzymes, allowing researchers to study enzyme activity and inhibition in a controlled environment.

Uses

Used in Biochemical Research:
BOC-VAL-PRO-ARG-AMC HCL is used as a fluorogenic substrate for studying the activity and inhibition of proteolytic enzymes, such as thrombin, in various assays. This allows researchers to gain insights into enzyme function, regulation, and potential therapeutic targets.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, BOC-VAL-PRO-ARG-AMC HCL is used as a tool for the development and testing of inhibitors targeting proteolytic enzymes. By using this substrate in assays, researchers can evaluate the efficacy and selectivity of potential drug candidates.
Used in Enzyme Inhibition Assays:
BOC-VAL-PRO-ARG-AMC HCL is used as a fluorogenic substrate in inhibitory assays with salivary protein cE5 and recombinant E. nipponicum serpinas. These assays help in understanding the interaction between the enzyme and its inhibitors, which is crucial for the development of effective therapeutic agents.
Used in Proteinase Assays:
In proteinase assays, BOC-VAL-PRO-ARG-AMC HCL serves as a substrate for studying the activity of hemolymph proteins. This allows researchers to investigate the role of these proteins in various biological processes and their potential as therapeutic targets.
Overall, BOC-VAL-PRO-ARG-AMC HCL is a versatile compound used across different industries for studying enzyme activity, developing inhibitors, and understanding the role of proteolytic enzymes in various biological processes.