70399-09-6

Basic information

• Product Name: 1 - fluoro - 4 - (propane - 2 - sulfonyl) - benzene
• Synonyms: p-Fluorphenyl-isopropylsulfon;1-fluoro-4-(propane-2-sulfonyl)-benzene;1-fluoro-4-(isopropylsulfonyl)benzene
• CAS NO: 70399-09-6
• Molecular Formula: C9H11FO2S
• Molecular Weight: 202.25
• Mol File: 70399-09-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1 - fluoro - 4 - (propane - 2 - sulfonyl) - benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1 - fluoro - 4 - (propane - 2 - sulfonyl) - benzene(70399-09-6)
• EPA Substance Registry System: 1 - fluoro - 4 - (propane - 2 - sulfonyl) - benzene(70399-09-6)

Safety Data

• Hazardous Substances Data: 70399-09-6(Hazardous Substances Data)

Usage

Description

1-fluoro-4-(propane-2-sulfonyl)benzene, with the chemical formula C9H11FO2S, is a benzene derivative featuring a fluoro substituent at the 1-position and a propane-2-sulfonyl substituent at the 4-position. 1 fluoro 4 (propane 2 sulfonyl) benzene is recognized for its reactivity and versatility in synthetic processes, making it a valuable component in the creation of various complex molecules.

Uses

Used in Pharmaceutical Synthesis:
1-fluoro-4-(propane-2-sulfonyl)benzene is used as an intermediate in the pharmaceutical industry for the synthesis of various drugs. Its unique structure and reactivity allow for the development of new medications with potential therapeutic benefits.
Used in Agrochemical Production:
In the agrochemical industry, 1-fluoro-4-(propane-2-sulfonyl)benzene serves as a crucial intermediate in the production of pesticides and other agricultural chemicals. Its incorporation into these products can enhance their effectiveness in protecting crops and improving overall agricultural yields.
Used in Dye and Pigment Manufacturing:
1 fluoro 4 (propane 2 sulfonyl) benzene is also utilized in the manufacture of dyes and pigments, where its chemical properties contribute to the creation of vibrant and stable colorants for various applications, including textiles, plastics, and printing inks.
Used in Organic Chemistry Research:
1-fluoro-4-(propane-2-sulfonyl)benzene holds potential applications in the field of organic chemistry as a building block for synthesizing more complex molecules. Its presence in research settings can lead to the discovery of novel compounds with diverse applications across multiple industries.

Upstream product

• 75-30-9 2-iodo-propane 
• 824-80-6 sodium 4-fluorobenzenesulfinate 
• 371-42-6 4-Fluorothiophenol 
• 702-13-6 4-(isopropylthio)-1-fluorobenzene 

Relevant articles and documents

P2X7R ANTAGONISTS

A compound has Formula I: (I). R1 is hydrogen, hydroxy, halogen, nitro, amino, alkyl, alkoxy, alkylamino, cycloalkyl, cycloalkyamino, heterocyclyl, aryl, heteroaryl, -NR7R8, -CO-R10, or -NH-CO-R10; L is a bond, a heterocyclic bivalent group, a heteroaromatic bivalent group, or an aromatic bivalent group; M is a bond, alkyl, aryl, heterocyclic bivalent group, heteroaromatic bivalent group, or aromatic bivalent group; X is a bond, -O-, -S-, -SO2-, -CO-, -NR9-, -(CH2)m-, or heterocyclic bivalent group, m is 1, 2, 3, 4, 5, or 6; Y is a bond, -NH-, heterocyclic bivalent group, heteroaromatic bivalent group, bivalent benzyl group, or aromatic bivalent group; and Z is hydrogen, halogen, alkyl, aryl, heterocyclyl, heteroaryl, -NR7R8, -CO-R10, or -NH-CO-R10; R7, R8, and R9 are independently hydrogen, hydroxy, halogen, nitro, amino, alkyl, alkoxy, alkylamino, cycloalkyl, cycloalkyamino, heterocyclyl, or heteroaryl; and R10 is -O-tert-butyl, -CH2CH2-phenyl, hydrogen, hydroxy, halogen, nitro, amino, alkyl, alkoxy, alkylamino, cycloalkyl, cycloalkyamino, heterocyclyl, or heteroaryl.

PHENOXY ACETIC ACID DERIVATIVES

The present invention provides phenoxyacetic acid derivatives of Formula (I) for the treatment of CRTH2 related disorders and disease selected from asthma, atopic dermatitis and inflammatory dermatoses.