Cas 70459-06-2,3-Quinolinecarboxylic acid, 7-chloro-6-fluoro-1,4-dihydro-1-methyl-4-oxo-, ethyl ester

70459-06-2

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Basic information

Product Name: 3-Quinolinecarboxylic acid, 7-chloro-6-fluoro-1,4-dihydro-1-methyl-4-oxo-, ethyl ester
Synonyms:
CAS NO:70459-06-2
Molecular Formula: C13H11ClFNO3
Molecular Weight: 283.687
EINECS: N/A
Product Categories: N/A
Mol File: 70459-06-2.mol
Article Data: 1

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: 3-Quinolinecarboxylic acid, 7-chloro-6-fluoro-1,4-dihydro-1-methyl-4-oxo-, ethyl ester(CAS DataBase Reference)
NIST Chemistry Reference: 3-Quinolinecarboxylic acid, 7-chloro-6-fluoro-1,4-dihydro-1-methyl-4-oxo-, ethyl ester(70459-06-2)
EPA Substance Registry System: 3-Quinolinecarboxylic acid, 7-chloro-6-fluoro-1,4-dihydro-1-methyl-4-oxo-, ethyl ester(70459-06-2)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 70459-06-2(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 70459-06-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,0,4,5 and 9 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 70459-06:
(7*7)+(6*0)+(5*4)+(4*5)+(3*9)+(2*0)+(1*6)=122
122 % 10 = 2
So 70459-06-2 is a valid CAS Registry Number.

70459-06-2Upstream product

86393-34-2 2,4-dichloro-5-fluorobenzoyl chloride

70459-06-2Downstream Products

70459-07-3 desethyleneciprofloxacin

70459-06-2Relevant articles and documents

Cycloaracylation of Enamines, I. - Synthesis of 4-Quinolone-3-carboxylic Acids

Grohe, Klaus,Heitzer, Helmut

, p. 29 - 37 (2007/10/02)

Starting with o-halobenzoyl chlorides 4 and open-chain secondary enamines 5, a new synthesis of 4-quinolone-3-carboxylic acids 12 is described.The reaction of 7-haloquinolone-3-carboxylic acids 12a-k with aliphatic amines 14 produces highly active antibacterial 7-aminoquinolone-3-carboxylic acids 15.The main product of the 1-cyclopropyl series, "ciprofloxacin" (15a), is being developed as a broad-spectrum chemotherapeutic agent.

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