70460-47-8

Basic information

• Product Name: 3-chloro-2-phenyl-2,3-dihydro-4H-chromen-4-one
• CAS NO: 70460-47-8
• Molecular Formula: C₁₅H₁₁ClO₂
• Molecular Weight: 258.6996
• Mol File: 70460-47-8.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 421.8°C at 760 mmHg
• Flash Point: 178°C
• Density: 1.31g/cm³
• Vapor Pressure: 2.54E-07mmHg at 25°C
• Refractive Index: 1.63
• CAS DataBase Reference: 3-chloro-2-phenyl-2,3-dihydro-4H-chromen-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-chloro-2-phenyl-2,3-dihydro-4H-chromen-4-one(70460-47-8)
• EPA Substance Registry System: 3-chloro-2-phenyl-2,3-dihydro-4H-chromen-4-one(70460-47-8)

Safety Data

• Hazardous Substances Data: 70460-47-8(Hazardous Substances Data)

Upstream product

• 75630-62-5 (Z)-α-chloro-2-hydroxychalcone 
• 75630-53-4 2'-hydroxychalcone dichloride 
• 1214-47-7 1-(2-hydroxyphenyl)-3-phenylprop-2-en-1-one 
• 39729-11-8 2'-hydroxychalcone dibromides 

Downstream Products

• 525-82-6 FLAVONE 

Relevant articles and documents

Pyrolitic Elimination of Hydrogen Halide and Halogen from 2,3-Dihalogenoketones

The thermal elimination of hydrogen chloride from 2'-hydroxychalcone dichlorides occured in two stages, initially forming 3-chloroflavones and then flavones; α-chloro-2'-hydroxychalcones, the likely intermediates in the formation of 3-chloroflavones, also yielded the same products.The pyrolysis of 2'-hydroxychalcone dibromides resulted in debromination as well as dehydrobromination with the consequent appearence of brominated flavones among the products.The formation of 3-bromoflavones was not observed but the isomeric (E)-α-bromo-2'-hydroxychalcones thermally isomerized to their (Z)-isomers and then underwent cyclization and dehydrobromination.The bromide were considerably more reactive than the dichlorides but, as a synthetic procedure, the pyrolysis of the dichlorides is cleaner and more productive.