70475-59-1Relevant articles and documents
Synthesis, biological evaluation, and docking studies of a novel sulfonamido-based gallate as pro-chondrogenic agent for the treatment of cartilage
Lin, Xiao,Chai, Ling,Liu, Buming,Chen, Hailan,Zheng, Li,Liu, Qin,Lin, Cuiwu
, (2017)
Gallic acid (GA) and its derivatives are anti-inflammatory agents and are reported to have potent effects on Osteoarthritis (OA) treatment. Nonetheless, it is generally accepted that the therapeutic effect and biocompatibility of GA is much weaker than it
Effect of a novel synthesized sulfonamido-based gallate-SZNTC on chondrocytes metabolism in vitro
Liu, Qin,Li, Mu-Yan,Lin, Xiao,Lin, Cui-Wu,Liu, Bu-Ming,Zheng, Li,Zhao, Jin-Min
, p. 127 - 138 (2014)
The ideal therapeutic agent for treatment of osteoarthritis (OA) should have not only potent anti-inflammatory effect but also favorable biological properties to restore cartilage function. Gallic acid (GA) and its derivatives are anti-inflammatory agents
Gallic acid hydrogen sulfide derivative and preparation method and medical application thereof
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Paragraph 0063; 0071; 0072, (2021/03/31)
The invention discloses a gallic acid hydrogen sulfide derivative and a preparation method and medical application thereof. The general formula of the gallic acid hydrogen sulfide derivative is A-Y-X,and A is gallic acid; Y is -C (O) O-, -C (O) NH-, -C (O) OC (O)-, -C (O) NHCH2 C (O)- or is absent, and when Y is absent, the compound is A-X; X is a moiety capable of releasing hydrogen sulfide alone or in combination with A. Compared with gallic acid and existing classic non-steroidal anti-inflammatory drugs, the gallic acid hydrogen sulfide derivative has the advantages that the anti-inflammatory activity is equivalent or enhanced, the side effects of gastrointestinal tracts and cardiovascular diseases are weakened, and the gallic acid hydrogen sulfide derivative has high anti-tumor activity and good cardiovascular and neuroprotective effects.
Syntheses, Structures, and Bioactivity Evaluation of some Transition Metal Complexes with Aroylbis(N,N-diethylthioureas) Derived from Natural Compounds
Thang Pham, Chien,Thuy Pham, Thu,Ha Nguyen, Viet,Nguyet Trieu, Thi,Huy Nguyen, Hung
, p. 1383 - 1391 (2021/05/21)
Two novel benzoylthioureas derived from gallic acid, (tri-O-acetyl)galloyl-N,N-diethylthiourea HL1, and cinnamic acid, cinnamoyl-N,N-diethylthiourea HL2 have been successfully prepared and characterized by means of elemental analysis
NOVEL α-TOCOPHEROL DERIVATIVES, AND COSMETIC USES OF THE SAME
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Paragraph 0076-0079, (2019/07/03)
The present invention relates to a novel andalpha;-tocopherol derivative compound and cosmetic uses thereof, more specifically, a compound represented by chemical formula 1. The present invention has an antioxidant activity as a novel compound and inhibits the activity of elastase, which is a degradation enzyme of elastin protein related to wrinkle formation of skin, thereby having an effect of alleviating skin wrinkles. In the chemical formula 1, n is 3, and R_1 is each independently hydrogen, a methyl group, or an acetyl group.COPYRIGHT KIPO 2019