70476-67-4

Basic information

• Product Name: 1,4-bis{[2-(diethylamino)ethyl]amino}-5,8-dihydroxyanthracene-9,10-dione
• Synonyms: 1,4-Bis((2-(diethylamino)ethyl)amino)-5,8-dihydroxy-9,10-anthracenedione; 9,10-Anthracenedione, 1,4-bis((2-(diethylamino)ethyl)amino)-5,8-dihydroxy-
• CAS NO: 70476-67-4
• Molecular Formula: C₂₆H₃₆N₄O₄
• Molecular Weight: 468.5884
• Mol File: 70476-67-4.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 692.5°C at 760 mmHg
• Flash Point: 372.6°C
• Density: 1.251g/cm³
• Vapor Pressure: 8.09E-20mmHg at 25°C
• Refractive Index: 1.643
• CAS DataBase Reference: 1,4-bis{[2-(diethylamino)ethyl]amino}-5,8-dihydroxyanthracene-9,10-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-bis{[2-(diethylamino)ethyl]amino}-5,8-dihydroxyanthracene-9,10-dione(70476-67-4)
• EPA Substance Registry System: 1,4-bis{[2-(diethylamino)ethyl]amino}-5,8-dihydroxyanthracene-9,10-dione(70476-67-4)

Safety Data

• Hazardous Substances Data: 70476-67-4(Hazardous Substances Data)

Upstream product

• 39837-47-3 (diethylamino)ethylamine 
• 23478-60-6 leuco-1,4,5,8-tetrahydroxyanthraquinone 
• 81-59-4 1,4,5,8-tetrahydroxy-2,3-dihydro-9,10-anthracenedione 
• 100-36-7 N,N-diethylethylenediamine 

Relevant articles and documents

Anti-cancer compounds

Compounds of formula (I) STR1 in which R1, R2, R3 and R4 are each separately selected from hydrogen, X, NH--A--NHR and NH--A--N(O)R'R" wherein X is hydroxy, halogeno, amino, C1-4 alkoxy or C2-8 alkanoyloxy, A is a C2-4 alkylene group with a chain length between NH and NHR or N(O)R'R" of at least 2 carbon atoms and R, R' and R" are each separately selected from C1-4 alkyl groups and C2-4 hydroxyalkyl and C2-4 dihydroxyalkyl groups in which the carbon atom attached to the nitrogen atom does not carry a hydroxy group and no carbon atom is substituted by two hydroxy groups, or R' and R" together are a C2-6 alkylene group which with the nitrogen atom to which R" and R" are attached forms a heterocyclic group having 3 to 7 atoms in the ring, but with the proviso that at least one of R1 to R4 is a group NH--A--N(O)R'R", and physiologically acceptable salts thereof are of value in the treatment of cancer.

1,4-Bis(substituted-amino)-5,8-dihydroxyanthraquinones and leuco bases thereof

This disclosure describes symmetrical 1,4-bis(substituted-amino)-5,8-dihydroxyanthraquinones useful as chelating agents and for inhibiting the growth of transplanted mouse tumors.