705302-73-4

Basic information

• Product Name: ethyl (R)-2-(benzyloxycarbonyl)amino-3-[(6-chloro-2-naphthalenylsulfonyl)amino]propionate
• Synonyms: ethyl (R)-2-(benzyloxycarbonyl)amino-3-[(6-chloro-2-naphthalenylsulfonyl)amino]propionate
• CAS NO: 705302-73-4
• Molecular Weight: 490.964
• Mol File: 705302-73-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ethyl (R)-2-(benzyloxycarbonyl)amino-3-[(6-chloro-2-naphthalenylsulfonyl)amino]propionate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl (R)-2-(benzyloxycarbonyl)amino-3-[(6-chloro-2-naphthalenylsulfonyl)amino]propionate(705302-73-4)
• EPA Substance Registry System: ethyl (R)-2-(benzyloxycarbonyl)amino-3-[(6-chloro-2-naphthalenylsulfonyl)amino]propionate(705302-73-4)

Safety Data

• Hazardous Substances Data: 705302-73-4(Hazardous Substances Data)

Upstream product

• 62234-37-1 2-(R)-amino>-3-aminopropionic acid 
• 102153-63-9 6-chloronaphth-2-ylsulfonyl chloride 

Relevant articles and documents

Synthesis and evaluation of 1-arylsulfonyl-3-piperazinone derivatives as factor Xa inhibitors III. Effect of ring opening of piperazinone moiety on inhibition

Compounds containing an ethylenediamine structure in place of the piperazine ring of M55113 (1) and M55551 (2) were synthesized to investigate the effects of a piperazine moiety and evaluated for activity as factor Xa (FXa) inhibitors. Most such compounds, however, exhibited lower activity (1/10-1/100) than that of M55113 and M55551 as FXa inhibitors.