70581-00-9

Basic information

• Product Name: 1-[4-(4-Pyridinyl)phenyl]-ethanone
• Synonyms: 1-[4-(4-Pyridinyl)phenyl]-ethanone;4-pyridin-4-yl-benzophenone;1-(4-(Pyridin-4-yl)phenyl)ethanone
• CAS NO: 70581-00-9
• Molecular Formula: C₁₃H₁₁NO
• Molecular Weight: 197.23254
• Mol File: 70581-00-9.mol
• Article Data: 12

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-[4-(4-Pyridinyl)phenyl]-ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[4-(4-Pyridinyl)phenyl]-ethanone(70581-00-9)
• EPA Substance Registry System: 1-[4-(4-Pyridinyl)phenyl]-ethanone(70581-00-9)

Safety Data

• Hazardous Substances Data: 70581-00-9(Hazardous Substances Data)

Usage

General Description

1-[4-(4-Pyridinyl)phenyl]-ethanone, also known as ACETOACET-PYRIDINE, is a chemical compound with the molecular formula C14H11NO. It is a yellowish powder with a molecular weight of 209.24 g/mol. 1-[4-(4-Pyridinyl)phenyl]-ethanone is used as a chemical intermediate in the synthesis of pharmaceuticals, agrochemicals, and dyes. It is also utilized in the production of UV-absorbing polymers and as a building block in organic synthesis. 1-[4-(4-Pyridinyl)phenyl]-ethanone has potential applications in various industries such as pharmaceuticals, agriculture, and materials science. However, it is important to handle and store this compound with care, as it can be harmful if ingested, inhaled, or absorbed through the skin.

Upstream product

• 1120-87-2 4-bromopyridin 
• 53578-00-0 2-(4-Bromophenyl)-2,2-dimethoxyethane 
• 626-61-9 4-Chloropyridine 
• 149104-90-5 4-acetylphenylboronic acid 
• 13329-40-3 4-Iodoacetophenone 
• 113964-72-0 triphenyl(pyridin-4-yl)phosphonium trifluoromethanesulfonate 
• 110-86-1 pyridine 
• 99-90-1 para-bromoacetophenone 
• 7379-35-3 4-chlorpyridine hydrochloride 
• 1104636-72-7 4-pyridylboronic acid MIDA ester 
• 1692-15-5 4-pyridylboronic acid 
• 25108-37-6 potassium pyridine-4-carboxylate 

Downstream Products

• 137103-81-2 1-(4-fluorophenyl)-1-<4-(4-pyridyl)phenyl>-1-ethanol 
• 142657-52-1 1-<4-(1,1-dimethoxyethyl)phenyl>-1-<4-(4-pyridyl)phenyl>-2-(1-imidazolyl)-1-ethanol 
• 137103-50-5 1-(4-trifluoromethylphenyl)-1-[4-(pyridin-4-yl)phenyl]-2-(1-imidazolyl)ethanol 
• 137103-68-5 2-Benzoimidazol-1-yl-1-(4-fluoro-phenyl)-1-(4-pyridin-4-yl-phenyl)-ethanol 
• 142657-51-0 Acetic acid 4-[1-hydroxy-2-imidazol-1-yl-1-(4-pyridin-4-yl-phenyl)-ethyl]-phenyl ester 
• 137103-84-5 Methanesulfonic acid 2-(4-fluoro-phenyl)-2-hydroxy-2-(4-pyridin-4-yl-phenyl)-ethyl ester 
• 142698-98-4 1-(4-Fluoro-phenyl)-2-morpholin-4-yl-1-(4-pyridin-4-yl-phenyl)-ethanol 
• 142657-50-9 1-Biphenyl-4-yl-2-imidazol-1-yl-1-(4-pyridin-4-yl-phenyl)-ethanol 
• 137103-67-4 1-(4-Dimethylamino-phenyl)-2-imidazol-1-yl-1-(4-pyridin-4-yl-phenyl)-ethanol 
• 137103-66-3 1-{4-[1-Hydroxy-2-imidazol-1-yl-1-(4-pyridin-4-yl-phenyl)-ethyl]-phenyl}-ethanone 
• 137103-74-3 1-(4-Hydroxymethyl-phenyl)-2-imidazol-1-yl-1-(4-pyridin-4-yl-phenyl)-ethanol 
• 142657-54-3 1-(4-Fluoro-phenyl)-1-(4-pyridin-4-yl-phenyl)-2-pyrrolidin-1-yl-ethanol 
• 137103-70-9 1-(4-Fluoro-phenyl)-1-(4-pyridin-4-yl-phenyl)-2-[1,2,4]triazol-1-yl-ethanol 
• 137103-71-0 1-(4-Fluoro-phenyl)-2-pyrazol-1-yl-1-(4-pyridin-4-yl-phenyl)-ethanol 

Relevant articles and documents

Magnetic chitosan-functionalized cobalt-NHC: Synthesis, characterization and catalytic activity toward Suzuki and Sonogashira cross-coupling reactions of aryl chlorides

Aryl chlorides are one of the most stable and available electrophiles, however, their coupling with nucleophiles remains a challenge in organic synthesis. Herein, we prepared a Cobalt-NHC (N-Heterocyclic carbene) complex anchored on magnetic chitosan nanoparticles and assayed its catalytic activity for the reactions of substituted phenylboronic acid and also phenlacetylene with derivatives of aryl chlorides. These reactions are of great importance since they are employed for the synthesis of unsymmetrical diarylethynes and biphenyls, which belong to a prime class of building blocks. The synthesized nanocatalyst was found to be highly efficient in Suzuki and Sonogashira coupling in terms of their activity and recyclability in polyethylene glycol (PEG) as a green reaction media under conditions of temperatures (70 and 100 °C) and Co loading (3 and 6 mol%). To the best of our knowledge, this is the first attempt of using cobalt-NHC complex for catalyzing the abovementioned reactions. Moreover, replacing the earth-abundant Cobalt-based catalyst as an alternative to high cost palladium make this approach promising from sustainable chemistry view.

Biaryl Cross-Coupling Enabled by Photo-Induced Electron Transfer

We report a protocol for aryl cross-coupling of electron-deficient aryl halides with electron-rich (hetero)arenes that is driven solely by violet light. This process takes advantage of formation of photo-excited state of electron-deficient aryl halides, that are reduced by electron-rich (hetero)arenes to form a pair of aryl anion and cation radicals. The resulting aryl anion radicals of aryl halides undergo mesolysis of the carbon-halogen bond to generate aryl radicals, that are coupled most likely with aryl cation radicals to afford functionalized biaryls. (Figure presented.).

One-dimensional chiral Cu (II) chain complex and its preparation method and use

The invention discloses a one-dimensional chiral Cu (II) chain complex and a preparation method thereof. The preparation method comprises firstly synthesizing a chiral organic ligand L, then synthesizing a chiral Cu (II) molecular building unit through co