705928-69-4Relevant articles and documents
Indium-mediated asymmetric allylation of acylhydrazones using a chiral urea catalyst
Tan, Kian L.,Jacobsen, Eric N.
, p. 1315 - 1317 (2007)
(Chemical Equation Presented) Urea-ka! A new role for urea-based chiral catalysts has been uncovered in the asymmetric allylation of acylhydrazones with allylindium reagents (see scheme; Bz: benzoyl). The best results were obtained using the bifunctional
Cascade reactions of glycine Schiff bases and chiral phase transfer catalysts in the synthesis of α-amino acids 3-substituted phthalides or isoindolinones
Perillo, Milena,Di Mola, Antonia,Filosa, Rosanna,Palombi, Laura,Massa, Antonio
, p. 4239 - 4246 (2014/01/17)
The tuning of aldol/cyclization cascade reactions of glycine Schiff bases with 2-cyano benzaldehydes provides access to non-natural α-amino acid derivatives substituted alternatively with phthalides or isoindolinones, depending on the strength of the used base. Moreover, a preliminary screening of catalysts and conditions for development of asymmetric versions identified chiral bifunctional phase transfer catalysts as particularly promising, leading to the α-amino esters 3-substituted phthalides in high yields and good diastereo- and enantioselectivity.
Development of novel chiral urea catalysts for the hetero-Michael reaction
Sohtome, Yoshihiro,Tanatani, Aya,Hashimoto, Yuichi,Nagasawa, Kazuo
, p. 477 - 480 (2007/10/03)
Chiral urea compounds 10a-g were synthesized as catalysts for conjugate addition of pyrrolidine (2) to γ-crotonolactone (3). In the presence of a catalytic amount of the chiral ureas, this hetero-Michael reaction was greatly accelerated. Asymmetric induct
