7067-87-0

Basic information

• Product Name: 1-(6-chloro-1,3-benzothiazol-2-yl)-4-[hydroxy(2-methylimidazo[1,2-a]pyridin-3-yl)methylidene]-5-pyridin-3-ylpyrrolidine-2,3-dione
• CAS NO: 7067-87-0
• Molecular Formula: C₁₅H₉FN₂S
• Molecular Weight: 501.9442
• Mol File: 7067-87-0.mol
• Article Data: 3

Chemical Properties

• Density: 1.59g/cm³
• Refractive Index: 1.8
• CAS DataBase Reference: 1-(6-chloro-1,3-benzothiazol-2-yl)-4-[hydroxy(2-methylimidazo[1,2-a]pyridin-3-yl)methylidene]-5-pyridin-3-ylpyrrolidine-2,3-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(6-chloro-1,3-benzothiazol-2-yl)-4-[hydroxy(2-methylimidazo[1,2-a]pyridin-3-yl)methylidene]-5-pyridin-3-ylpyrrolidine-2,3-dione(7067-87-0)
• EPA Substance Registry System: 1-(6-chloro-1,3-benzothiazol-2-yl)-4-[hydroxy(2-methylimidazo[1,2-a]pyridin-3-yl)methylidene]-5-pyridin-3-ylpyrrolidine-2,3-dione(7067-87-0)

Safety Data

• Hazardous Substances Data: 7067-87-0(Hazardous Substances Data)

Upstream product

• 136-95-8 2-amino-benzthiazole 
• 357952-79-5 1-(4-fluorophenyl)-2-(p-tolylsulfonyloxy)ethanone 
• 403-29-2 2-bromo-4'-fluoroacetophenone 
• 99582-77-1 1-(4-Fluoro-phenyl)-2-(2-imino-benzothiazol-3-yl)-ethanone; hydrobromide 

Relevant articles and documents

Metal-free oxidative decarbonylative halogenation of fused imidazoles

An efficient strategy has been developed for the deformylative halogenation of carbaldehyde imidazo-fused heterocycles in the presence of TBHP controlled by temperature. A convenient and sequential functionalization (C8 to C3) portrays the synthetic utility of the current method.N-Heterocycle benzamide products were also observedviathe ring opening of imidazopyridines through the cleavage of C-C bond at high temperatures. Features of this method include temperature-controlled excellent regioselectivity, mild conditions and functional group tolerance.

Imidazobenzothiazoles. 2. New Immunosuppressive Agents

A series of 2-phenylimidazobenzothiazole derivatives was prepared and tested for immunological activities.Some of the compounds showed significant suppressive activity of delayed type hypersensitivity (DTH) without inhibition of humoral immunity in mice by oral administration.The most active compound was 2-(m-hydroxyphenyl)imidazobenzothiazole (20).