706791-85-7

Basic information

• Product Name: 1,1-dimethylethyl 3-bromo-5-(1,1-dioxidotetrahydro-2H-1,2-thiazin-2-yl)benzoate
• Synonyms: 1,1-dimethylethyl 3-bromo-5-(1,1-dioxidotetrahydro-2H-1,2-thiazin-2-yl)benzoate
• CAS NO: 706791-85-7
• Molecular Weight: 390.298
• Mol File: 706791-85-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1,1-dimethylethyl 3-bromo-5-(1,1-dioxidotetrahydro-2H-1,2-thiazin-2-yl)benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1-dimethylethyl 3-bromo-5-(1,1-dioxidotetrahydro-2H-1,2-thiazin-2-yl)benzoate(706791-85-7)
• EPA Substance Registry System: 1,1-dimethylethyl 3-bromo-5-(1,1-dioxidotetrahydro-2H-1,2-thiazin-2-yl)benzoate(706791-85-7)

Safety Data

• Hazardous Substances Data: 706791-85-7(Hazardous Substances Data)

Upstream product

• 37441-50-2 1,4-butanesultam 
• 690260-92-5 3-bromo-5-iodobenzoic acid tert-butyl ester 

Downstream Products

• 706792-21-4 1,1-dimethylethyl 3-(1,1-dioxidotetrahydro-2H-1,2-thiazin-2-yl)-5-[(1E/Z)-1-propen-1-yl]benzoate 
• 706791-93-7 1,1-dimethylethyl 3-(1,1-dioxidotetrahydro-2H-1,2-thiazin-2-yl)-5-[ethyl(phenylmethyl)amino]benzoate 

Relevant articles and documents

3-(1,1-DIOXOTETRAHYDRO-1,2-THIAZIN-2-YL) or 3-(1,1-DOXO-ISOTHIAZOLIDIN-2YL) SUBSTITUTED BENZAMIDE COMPOUNDS AS ASP2 INHIBITORS

The present invention relates to hydroxyethylene compounds of formula (I); having A sp2 (β-secretase, BACE1 or Memapsin) inhibitory activity, processes for their preparation, to compositions containing them and to their use in the treatment of diseases characterized by elevated β-amyloid levels or β-amyloid deposits, particularly Alzheimer's disease wherein R1 represents a group of formula Zc.