70723-31-8

Basic information

• Product Name: (Z)-α-(benzamido)-β-(4-hydroxy-3-methoxyphenyl)acrylic acid
• Synonyms: (Z)-α-(benzamido)-β-(4-hydroxy-3-methoxyphenyl)acrylic acid
• CAS NO: 70723-31-8
• Molecular Weight: 313.31
• Mol File: 70723-31-8.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: (Z)-α-(benzamido)-β-(4-hydroxy-3-methoxyphenyl)acrylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-α-(benzamido)-β-(4-hydroxy-3-methoxyphenyl)acrylic acid(70723-31-8)
• EPA Substance Registry System: (Z)-α-(benzamido)-β-(4-hydroxy-3-methoxyphenyl)acrylic acid(70723-31-8)

Safety Data

• Hazardous Substances Data: 70723-31-8(Hazardous Substances Data)

Upstream product

• 495-69-2 Hippuric Acid 
• 121-33-5 vanillin 
• 1199-01-5 2-phenylazlactone 
• 71413-82-6 (Z)-2-methoxy-4-((5-oxo-2-phenyloxazol-4(5H)-ylidene)methyl)phenyl acetate 
• 30037-41-3 N-benzoyl-3-(4-hydroxy-3-methoxyphenyl)-(S)-phenylalanine 
• 71198-75-9 (Z)-4-(4-hydroxy-3-methoxybenzylidene)-2-phenyloxazolin-5(4H)-one 

Downstream Products

• 138867-57-9 N-benzoyl-3-(4-hydroxy-3-methoxyphenyl)-(R)-alanine 
• 138867-54-6 N-benzoyl-3-(4-hydroxy-3-methoxyphenyl)-(S)-alanine 
• 30037-41-3 N-benzoyl-3-(4-hydroxy-3-methoxyphenyl)-(S)-phenylalanine 
• 35144-07-1 N-benzoyl-3-(4-hydroxy-3-methoxyphenyl)-(R)-phenylalanine 
• 2901-78-2 N-benzoyl-4-hydroxy-3-methoxy-phenylalanine 

Relevant articles and documents

A modified synthesis of (±)-β-aryllactic acids

The synthesis of racemic forms of the reportedly active principle of Danshen, namely (±)-β-(3,4-dihydroxyphenyl)lactic acid [(±)3-(3,4-dihydroxyphenyl)-2-hydroxypropanoic acid] and its seven racemic derivatives is reported.

SYNTHESIS AND RESOLUTION OF A NEW TYPE OF CHIRAL BISPHOSPHINE LIGAND, trans-BIS-1,2-(DIPHENYLPHOSPHINO) CYCLOBUTANE, AND ASYMMETRIC HYDROGENATION USING ITS RHODIUM COMPLEX

Oxidative coupling of the 1,4-dicarbanions derived from bis-1,4-(diphenylphosphinyl) butane gave (+/-)-trans-bis-1,2-(diphenyl-phosphinyl) cyclobutane.Asymmetric hydrogenation of dehydroamino acids using rhodium complex of the optically active bisphosphin

Asymmetric Catalyses. V. Enantioselective Amino Acid Synthesis by Hydrogenation of Prochiral Olefins with Rh-Complexes of the New Optically Active Chelating Phosphane Norphos

Racemic bicyclohept-5-ene-2,3-diylbis(diphenylphosphane oxide), NorphosO, can be resolved with (-)-di-O-benzoyltartaric acid, (-)-DBW.The X-ray structure analysis of the diastereomer (-)-NorphosO/(-)-DBW, which is less soluble in ethanol, exhibits strong hydrogen bonds between the carboxylic groups of DBW and the PO groups.The bonding of the DBW-carboxylic groups to different NorphosO units leads to the formation of infinite close-packed chains.From the internal comparison with (-)-DBW the absolute configuration follows as (2R,3R) for (-)-Norphos.The chelating phosphanes (+)- and (-)-Norphos, obtained by SiHCl3-reduction of (+)- and (-)-NorphosO, respectively, afford neutral and cationic Rh-complexes which, with H2 at room temperature and atmospheric pressure within a few hours, give quantitative hydrogenation of α-(acetylamino)cinnamic acid, α-(acetylamino)acrylic acid and Dopa precursors.The optical yields vary between 79 and 97percent.