7074-12-6

Basic information

• Product Name: 3-(4-methoxyphenyl)butan-2-one
• CAS NO: 7074-12-6
• Molecular Formula: C₁₁H₁₄O₂
• Molecular Weight: 178.2277
• Mol File: 7074-12-6.mol
• Article Data: 20

Chemical Properties

• Boiling Point: 260.6°C at 760 mmHg
• Flash Point: 104.3°C
• Density: 1.006g/cm³
• Vapor Pressure: 0.0121mmHg at 25°C
• Refractive Index: 1.496
• CAS DataBase Reference: 3-(4-methoxyphenyl)butan-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-methoxyphenyl)butan-2-one(7074-12-6)
• EPA Substance Registry System: 3-(4-methoxyphenyl)butan-2-one(7074-12-6)

Safety Data

• Hazardous Substances Data: 7074-12-6(Hazardous Substances Data)

Upstream product

• 261930-06-7 1-(4-methoxyphenyl)-1,2-dihydroxy-2-methylpropane 
• 122-84-9 4-methoxybenzyl methyl ketone 
• 74-88-4 methyl iodide 
• 917-64-6 methyl magnesium iodide 
• 31007-06-4 2-(4-methoxyphenyl)propionitrile 
• 104174-19-8 3-(4-Methoxy-phenyl)-2-butanol 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 4091-39-8 3-chloro-2-butanone 
• 77-78-1 dimethyl sulfate 
• 15482-31-2 1-hydroxy-1-methyl-1-(4'-methoxyphenyl)-2-propanone 
• 696-62-8 para-iodoanisole 
• 598-32-3 2-hydroxy-3-butene 
• 7142-71-4 2-(4-methoxyphenyl)butane-2,3-diol 
• 51431-73-3 1-(but-2-en-2-yl)-4-methoxybenzene 

Downstream Products

• 77525-91-8 1-methoxy-4-(1-methoxy-ethyl)-benzene 
• 104741-73-3 Methyl-p-anisyl-carbinol-methylaether 
• 100-06-1 1-(4-methoxyphenyl)ethanone 
• 118452-62-3 3-methyl-3-(p-methoxyphenyl)-5-(phenylsulfinyl)-2-pentanone 
• 31007-14-4 β-Acetyl-β-(p-methoxyphenyl)-buttersaeure 
• 35144-34-4 erythro-3-(4-methoxyphenyl)butan-2-ol 
• 35144-34-4 threo-3-(4-methoxyphenyl)butan-2-ol 
• 91633-30-6 1-(1-azidoethyl)-4-methoxybenzene 
• 82638-98-0 Trifluoro-acetic acid 1-(4-methoxy-phenyl)-ethyl ester 
• 1309380-88-8 C₁₈H₂₁NO₅S 

Relevant articles and documents

Metal Free, Direct and Selective Deoxygenation of α-Hydroxy Carbonyl Compounds: Access to α,α-Diaryl Carbonyl Compounds

An efficient, metal free, direct and selective deoxygenation of α-hydroxy carbonyl compounds is achieved with the aid of catalytic amount of aqueous HClO4 (70 %) and triethylsilane as hydride source. A variety of α-hydroxy-α,α-diaryl carbonyl compounds are selectively deoxygenated to give α,α-diaryl carbonyl compounds in good to excellent yields. Intermediacy of α-keto carbenium ion is proposed on the basis of some control experiments and atmospheric pressure chemical ionization mass spectral analysis.

Ni-Catalyzed Reductive C-O Bond Arylation of Oxalates Derived from α-Hydroxy Esters with Aryl Halides

A Ni-catalyzed reductive cross-coupling of α-hydroxycarbonyl compounds modified with oxalyl groups and aryl halides has been developed that furnishes α-aryl esters under mild conditions and tolerates a variety of functionalized aryl halides bearing electron-withdrawing and -donating groups. This work highlights C-O bond fragmentation on secondary alkyl carbon centers that generates α-carbonyl radicals.

Regioselective 1,2-Diol Rearrangement by Controlling the Loading of BF3·Et2O and Its Application to the Synthesis of Related Nor-Sesquiterene- and Sesquiterene-Type Marine Natural Products

The regiocontrolled rearrangement of 1,2-diols has been achieved by controlling the loading of BF3·Et2O. Its applicability is showcased by the divergent synthesis of austrodoral, austrodoric acid, and 8-epi-11-nordriman-9-one, as well as a formal synthesis of siphonodictyal B and liphagal. A new light is shed on piancol-type rearrangements that will be useful in diversity-oriented synthesis of related natural products.