70741-38-7 Usage
Description
(3S,10S,13R,14R,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,11,12,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-ol is a complex organic compound with a unique molecular structure. It is characterized by its stereochemistry, with specific configurations at the 3rd, 10th, 13th, 14th, and 17th carbon atoms. (3S,10S,13R,14R,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,11,12,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-ol belongs to the class of cyclopenta[a]phenanthrenols, which are known for their diverse biological activities and potential applications in various fields.
Uses
1. Used in Pharmaceutical Industry:
(3S,10S,13R,14R,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,11,12,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-ol is used as a pharmaceutical compound for its potential therapeutic effects. (3S,10S,13R,14R,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,11,12,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-ol's unique structure may allow it to interact with specific biological targets, such as receptors or enzymes, which could lead to the development of new drugs for various diseases.
2. Used in Chemical Research:
(3S,10S,13R,14R,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,11,12,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-ol is also used in chemical research as a starting material or intermediate for the synthesis of other complex organic molecules. Its unique stereochemistry and functional groups make it a valuable tool for studying reaction mechanisms and developing new synthetic methods.
3. Used in Material Science:
(3S,10S,13R,14R,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,11,12,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-ol's structural properties may also make it suitable for use in the development of new materials with specific properties, such as improved stability, solubility, or reactivity. It could be used as a component in the design of advanced materials for various applications, including electronics, coatings, or adhesives.
Check Digit Verification of cas no
The CAS Registry Mumber 70741-38-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,0,7,4 and 1 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 70741-38:
(7*7)+(6*0)+(5*7)+(4*4)+(3*1)+(2*3)+(1*8)=117
117 % 10 = 7
So 70741-38-7 is a valid CAS Registry Number.
InChI:InChI=1/C27H44O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h9,18-19,21,23-24,28H,6-8,10-17H2,1-5H3/t19-,21+,23-,24?,26+,27-/m1/s1
70741-38-7Relevant articles and documents
Comprehensive gas chromatography-electron ionisation mass spectrometric analysis of fatty acids and sterols using sequential one-pot silylation: Quantification and isotopologue analysis
Kloos, Dick-Paul,Gay, Emmanuel,Lingeman, Henk,Bracher, Franz,Mueller, Christoph,Mayboroda, Oleg A,Deelder, Andre M,Niessen, Wilfried M A,Giera, Martin
, p. 1507 - 1514 (2014/06/10)
RATIONALEFatty acids and sterol lipids play crucial roles in several biological processes and several biological facts underline the interconnection between these lipid classes. Therefore, it is of interest to develop a comprehensive method analysing both classes in the form of their most favourable derivatives suitable for quantification and isotopologue analysis. METHODSLipids were derivatised by a sequential one-pot procedure using N-tert-butyldimethylsilyl-N-methyltrifluoroacetamide (MtBSTFA) and N,O-bis(trimethylsilyl)trifluoroacetamide (BSTFA). No clean-up or concentration steps were necessary. The prepared samples were directly available for gas chromatography-electron ionisation mass spectrometric (GC-EI-MS) analysis on a standard column. For quantification, the SIM mode was used and for isotopologue analysis scheduled scan mode was applied. RESULTSDevelopment of a sequential one-pot derivatisation for GC-EI-MS allowing comprehensive analysis of fatty acids and sterols as their most favourable derivatives. Validation carried out using human plasma, comparison with certified NIST plasma. LLOQ of usually 3.3 ng/mL achieved. Isotopologue analysis of 2-[13C]-acetate incorporation in HL-60 cells proving feasibility of method. CONCLUSIONSThe presented method successfully combines two consecutive silylation reactions in one pot, enabling the analysis of both fatty acids and sterols in a comprehensive analytical method. The method has great potential for the quantification of lipids as well as the comprehensive study of both biochemical pathways, using [13C]-flux analysis. Copyright