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708273-57-8

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708273-57-8 Usage

General Description

4-Hydroxy-4-(6-methoxypyridin-3-yl)cyclohexanone is a chemical compound with the molecular formula C12H15NO3. It is a derivative of cyclohexanone and contains a hydroxy group and a methoxy-substituted pyridine ring. 4-Hydroxy-4-(6-methoxypyridin-3-yl)cyclohexanone is commonly used in the pharmaceutical industry for its potential medicinal properties and is under research for its anti-inflammatory and antioxidant effects. It has also been studied for its potential application in the treatment of neurodegenerative diseases such as Alzheimer's and Parkinson's. Its structure and properties make it a valuable target for further investigation in drug development and therapeutic applications.

Check Digit Verification of cas no

The CAS Registry Mumber 708273-57-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,0,8,2,7 and 3 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 708273-57:
(8*7)+(7*0)+(6*8)+(5*2)+(4*7)+(3*3)+(2*5)+(1*7)=168
168 % 10 = 8
So 708273-57-8 is a valid CAS Registry Number.
InChI:InChI=1/C12H15NO3/c1-16-11-3-2-9(8-13-11)12(15)6-4-10(14)5-7-12/h2-3,8,15H,4-7H2,1H3

708273-57-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-hydroxy-4-(6-methoxypyridin-3-yl)cyclohexan-1-one

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:708273-57-8 SDS

708273-57-8Relevant articles and documents

CHEMOKING RECEPTOR ANTAGONISTS

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Page/Page column 217, (2013/03/26)

Disclosed herein are chemokine receptor antagonists of formula (I) wherein G1, X1, X2, and X3 are as defined in the specification. Compositions comprising such compounds; and methods for treating conditions and disorders using such compounds and compositions are also described.

Discovery of INCB3284, a potent, selective, and orally bioavailable hCCR2 antagonist

Xue, Chu-Biao,Feng, Hao,Cao, Ganfeng,Huang, Taisheng,Glenn, Joseph,Anand, Rajan,Meloni, David,Zhang, Ke,Kong, Lingquan,Wang, Anlai,Zhang, Yingxin,Zheng, Changsheng,Xia, Michael,Chen, Lihua,Tanaka, Hiroyuki,Han, Qi,Robinson,Modi, Dilip,Storace, Lou,Shao, Lixin,Sharief, Vaqar,Li, Mei,Galya, Laurine G.,Covington, Maryanne,Scherle, Peggy,Diamond, Sharon,Emm, Tom,Yeleswaram, Swamy,Contel, Nancy,Vaddi, Kris,Newton, Robert,Hollis, Greg,Friedman, Steven,Metcalf, Brian

supporting information; experimental part, p. 450 - 454 (2011/08/22)

We report the identification of 13 (INCB3284) as a potent human CCR2 (hCCR2) antagonist. INCB3284 exhibited an IC50 of 3.7 nM in antagonism of monocyte chemoattractant protein-1 binding to hCCR2, an IC 50 of 4.7 nM in antagonism of c

4-AZETIDINYL-1-HETEROARYL-CYCLOHEXANOL ANTAGONISTS OF CCR2

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Page/Page column 25, (2010/06/19)

The present invention comprises compounds of Formula (I). wherein: R1, R2, R3, and R4 are as defined in the specification. The invention also comprises pharmaceutical compositions comprising the compounds of formula (I) and methods of preventing, treating or ameliorating a CCR2 mediated syndrome, disorder or disease, for example, type II diabetes, obesity or asthma, by administering the compounds of formula (I).

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