709649-71-8Relevant articles and documents
Rational design of novel CYP2A6 inhibitors
Tani, Niina,Juvonen, Risto O.,Raunio, Hannu,Fashe, Muluneh,Lepp?nen, Jukka,Zhao, Bin,Tyndale, Rachel F.,Rahnasto-Rilla, Minna
, p. 6655 - 6664 (2015/02/19)
Inhibition of CYP2A6-mediated nicotine metabolism can reduce cigarette smoking. We sought potent and selective CYP2A6 inhibitors to be used as leads for drugs useful in smoking reduction therapy, by evaluating CYP2A6 inhibitory effect of novel formyl, alk