70978-88-0Relevant articles and documents
Preparation and application of aminourea-sensitive amine oxidase inhibitor
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Paragraph 0223-0224; 0228-0230, (2020/04/17)
The invention provides preparation and application of an aminourea-sensitive amine oxidase inhibitor. Specifically, the invention discloses a compound as shown in a formula I which is described in thespecification or a stereoisomer or racemate or a pharmaceutically acceptable salt thereof. The invention also discloses the capability of the compound in inhibition of aminourea-sensitive amine oxidase.
Nonpeptide Renin Inhibitors Employing a Novel 3-Aza(or oxa)-2,4-dialkyl Glutaric Acid Moiety as a P2/P3 Amide Bond Replacement
Baker, William R.,Fung, Anthony K. L.,Kleinert, Hollis D.,Stein, Herman H.,Plattner, Jacob J.,et al.
, p. 1722 - 1734 (2007/10/02)
A new series of renin inhibitors has been developed.The inhibitors feature a novel replacement for the P2/P3 dipeptide moiety normally associated with renin inhibitors.The dipeptide replacement was a (2S,4S)-3-aza(or oxa)-2,4-dialkylglutaric acid amide.Ex
Antihypertensive 4-amino-2-[4-(substituted-alkoxy)piperidino)]quinazolines
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, (2008/06/13)
Regulators of the cardiovascular system and, in particular, in the treatment of hypertension having the formula STR1 pharmaceutically-acceptable bioprecursors thereof, and the pharmaceutically-acceptable acid addition salts thereof; wherein each of R